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Patent Searching and Data


Title:
PRODUCTION OF THIENOPYRIDINE DERIVATIVE
Document Type and Number:
Japanese Patent JPS61271291
Kind Code:
A
Abstract:

PURPOSE: To obtain chlorobenzyl-tetrahydro-thieno[3,2-C]pyridine useful as an agent for suppressing the coagulation and agglutination of platelet, by reacting tetrahydro-thieno-pyridine with a chlorobenzyl derivative in the presence of an organic tertiary amine.

CONSTITUTION: The objective 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-C]pyri d-ine of formula II and its salt can be produced by reacting (A) 1 mol of 4,5,6,7- tetrahydro-thieno[3,2-C]pyridine with (B) preferably 0.5W1mol of a 2-chlorobenzyl derivative in the presence of an organic tertiary amine (preferably triethylamine or pyridine) usually in a solvent such as acetonitrile, benzene, etc., preferably at 20W30°C.


Inventors:
YAMANOCHI TAKENAGA
Application Number:
JP11206385A
Publication Date:
December 01, 1986
Filing Date:
May 27, 1985
Export Citation:
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Assignee:
ASAHI CHEMICAL IND
International Classes:
C07D493/18; C07D495/04; (IPC1-7): C07D495/04