Title:
PROGNOSIS DIAGNOSING MARKER FOR PREDICTING TREATMENT RESPONSE AND/OR SURVIVAL TIME OF PATIENT SUFFERING FROM MAMMARY CELL GROWTH DISORDER
Document Type and Number:
Japanese Patent JP2005224238
Kind Code:
A
Abstract:
To provide a method for conducting diagnosis of prognosis and/or prediction of result of estrogenic treatment of a patient suffering from mammary cell growth disorder, especially, mastocarcinoma.
This method determines an expression level of a gene PITX2 of a mammary cell, genetic variation of a genomic DNA related to the PITX2, or epigenetic variation thereof, wherein a specific base sequence derived from breast cancer, an oligonucleotide, and an antibody are used.
Inventors:
FOEKENS JOHN
HARBECK NADJA
KOENIG THOMAS
MAIER SABINE
MARTENS JOHN
MODEL FABIAN
NIMMRICH INKO
RUJAN TAMAS
SCHMITT MANFRED
LESCHE RALF
DIETRICH DIMO
MUELLER VOLKMAR
KLUTH ANTJE
SCHWOPE INA
HARTMANN OLIVER
ADORJAN PETER
HARBECK NADJA
KOENIG THOMAS
MAIER SABINE
MARTENS JOHN
MODEL FABIAN
NIMMRICH INKO
RUJAN TAMAS
SCHMITT MANFRED
LESCHE RALF
DIETRICH DIMO
MUELLER VOLKMAR
KLUTH ANTJE
SCHWOPE INA
HARTMANN OLIVER
ADORJAN PETER
Application Number:
JP2004361965A
Publication Date:
August 25, 2005
Filing Date:
December 14, 2004
Export Citation:
Assignee:
EPIGENOMICS AG
International Classes:
C12N15/09; C12Q1/68; (IPC1-7): C12N15/09; C12Q1/68
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Shinobu
Furudate Kutanko
Yuriko Shinobu
Furudate Kutanko