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Title:
PURIFICATION OF IMMUNOGLOBULIN M
Document Type and Number:
Japanese Patent JP2945181
Kind Code:
B2
Abstract:

PURPOSE: To purify efficiently immunoglobulin M in high speed and purity.
CONSTITUTION: The immunoglobulin M alone can be selectively recovered in high efficiency by the following consecutive processes: (1) prior to chromatographic treatment, the nucleic acid in a liquid to be treated is removed, and (2) the resulting liquid's purification by affinity chromatography with protamine as immobilized phase on a high-performance affinity carrier with silica gel or a porous polymer as substrate.


Inventors:
ASANO SHINICHI
YAMADA SAICHI
Application Number:
JP20984091A
Publication Date:
September 06, 1999
Filing Date:
July 26, 1991
Export Citation:
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Assignee:
NIPPON GAISHI KK
International Classes:
A61K39/395; B01D15/08; C07K1/16; C07K1/22; C07K14/00; C07K16/00; C12P21/08; G01N33/531; C12R1/91; (IPC1-7): C07K16/00; C07K1/22; C12P21/08
Domestic Patent References:
JP2493A
Foreign References:
Other References:
Biochim.Biophys.Acta,Vol.490,No.2(1977)p.363−369
Attorney, Agent or Firm:
名嶋 明郎 (外2名)