Title:
ピリジン並びに5員芳香環系化合物、その製造方法及び使用
Document Type and Number:
Japanese Patent JP6816287
Kind Code:
B2
Abstract:
The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.
Inventors:
Chen, Shuishin
Kon, May Yui
Cian, Ray
Chen, Yi
Tsao, Chiang Hoa
Jiang, Jiang
Shen, Chiang Chien
Tin, chien
Yao, Yutzai
Chao, Chao
Zion, Ewan Fan
Kon, May Yui
Cian, Ray
Chen, Yi
Tsao, Chiang Hoa
Jiang, Jiang
Shen, Chiang Chien
Tin, chien
Yao, Yutzai
Chao, Chao
Zion, Ewan Fan
Application Number:
JP2019533273A
Publication Date:
January 20, 2021
Filing Date:
September 06, 2017
Export Citation:
Assignee:
SHANGHAI HAIHE PHARMACEUTICAL CO., LTD
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
International Classes:
C07D471/04; A61K31/444; A61K31/4545; A61K31/496; A61K31/5377; A61P35/00; A61P37/02; C07D519/00
Domestic Patent References:
JP2014534178A | ||||
JP60172979A | ||||
JP2001278756A | ||||
JP2006503060A | ||||
JP2013544840A | ||||
JP2013528591A | ||||
JP2014511389A | ||||
JP2015501784A |
Foreign References:
WO2016102493A1 | ||||
WO2010113942A1 |
Other References:
Tetrahedron (2006), Vol.62, p.3798-3808
Journal of Organic Chemistry (1978), Vol.43, No.14, p.2900-2906
Journal of Organic Chemistry (1978), Vol.43, No.14, p.2900-2906
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation