To provide a new pyrroloquinoline compound useful as a medicine, its pharmaceutically tolerable salt, and their production methods.
This invention provides a pyrroloquinoline compound represented by formula (1) [wherein R1 is nitro, cyano, a halogen or the like; m is 0, 1, 2 or 3; R2 and R3 are each H or the like; R4 is H, a 1-6C alkyl, a 3-8C cycloalkyl, an optionally substituted phenyl or benzyl group, an optionally substituted saturated or unsaturated heterocyclic group containing 1-4 N, O or S atoms or the like; and R5 is an optionally substituted phenyl group, a saturated or unsaturated heterocyclic group containing 1-4 optionally substituted N, O or S atoms or a group represented by C(=O)r6, CH=CHr6 or (CH2)nr6 (wherein r6 is a 1-6C alkoxy or the like)]; its pharmaceutically tolerable salt; and their production methods.
UMEDA NOBUHIRO
UCHIDA SEIICHI