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Title:
QUINOLINE DERIVATIVE AS TYROSINE KINASE INHIBITOR
Document Type and Number:
Japanese Patent JP2007191486
Kind Code:
A
Abstract:

To provide various chemical substances useful for the treatment with VEGF-RTK antagonist.

The organic compound is expressed by structural formula I or II wherein the variable groups are specifically defined. The invention further relates to a pharmaceutical formulation containing the organic compound, its pharmaceutically acceptable salt and a pharmaceutically acceptable carrier. The pharmaceutical formulation is prepared by mixing the organic compound or its pharmaceutically acceptable salt with a carrier and water. The method for the treatment of a patient contains the administration of the pharmaceutical formulation to the patient to be treated.

COPYRIGHT: (C)2007,JPO&INPIT


Inventors:
RENHOWE PAUL
PECCHI SABINA
MACHAJEWSKI TIM
SHAFER CYNTHIA
TAYLOR CLARKE
MCCREA BILL
MCBRIDE CHRIS
JAZAN ELISA
Application Number:
JP2007062683A
Publication Date:
August 02, 2007
Filing Date:
March 12, 2007
Export Citation:
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Assignee:
CHIRON CORP
International Classes:
C07D243/08; A61K31/19; C07D401/14; A61K31/4709; A61K31/4745; A61K31/496; A61K31/513; A61K31/5377; A61K31/541; A61K31/551; A61P9/00; A61P35/00; A61P43/00; C07D401/04; C07D403/04; C07D405/04; C07D405/14; C07D409/04; C07D409/14; C07D413/04; C07D413/14; C07D417/04; C07D453/02; C07D471/04; C07D487/08; C07D487/18; C07D519/00
Domestic Patent References:
JP4361727B22009-11-11
Attorney, Agent or Firm:
Shusaku Yamamoto
Takamura Yasumura
Morishita Natsuki