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Title:
REAGENT AND METHOD FOR PREPARING LPS ANTAGONIST B1287 AND STEREOISOMER THEREOF
Document Type and Number:
Japanese Patent JP2011037885
Kind Code:
A
Abstract:

To provide methods for preparing LPS (linear programming system) antagonist lipodisaccharide B1287 and stereoisomers thereof.

The invention provides methods for preparing LPS antagonist lipodisaccharide B1287 useful in the prophylactic and affirmative treatment of endotoxemia shown by formula, and stereoisomers thereof. Also there are provided useful synthetic intermediates.


Inventors:
FAN RULIN
Application Number:
JP2010000230114
Publication Date:
February 24, 2011
Filing Date:
October 12, 2010
Export Citation:
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Assignee:
EISAI R&D MAN CO LTD
International Classes:
C07H1/02; A61K31/7024; A61P7/00; A61P31/04; C07H3/04; C07H9/04; C07H15/04; C07H15/12
Domestic Patent References:
JPH05194470A1993-08-03
JPH11506793A1999-06-15
Foreign References:
WO2001037843A12001-05-31
WO1997011708A11997-04-03
Other References:
JPN6013062975; PROTEVTIVE GROUPS IN ORGANIC SYNTHESIS , 1991, p.309-311,321,351, JOHN WILEY & SONS, INC.
Attorney, Agent or Firm:
山本 秀策
安村 高明
森下 夏樹