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Patent Searching and Data


Title:
SIGB
Document Type and Number:
Japanese Patent JPH11155575
Kind Code:
A
Abstract:

To obtain the subject polynucleotide capable of inducing an immunological response to bacteria esp. Staphylococcus and useful for any treatment and prevention using a genetic immunity treatment.

This polynucleotide is either a polynucleotide SigB (including any complementary polynucleotides thereto) having the sameness of at least 70% with a polynucleotide encoding a polypeptide [a new sigma SigB derived from Staphylococcus aureus] having the amino acids 1 to 256 of the formula or a polynucleotide having at least 15 continuous bases in the above polynucleotide. This polynucleotide may be obtained by using such a standard cloning and screening method as to subject a chromosome DNA fragment from S. aureus WCUH29 to cloning and sequence determination and obtain clone with the full length.


Inventors:
FOSBERRY ANDREW P
LAWLOR ELIZABETH J
NICHOLAS RICHARD O
Application Number:
JP1997000330755
Publication Date:
June 15, 1999
Filing Date:
October 23, 1997
Export Citation:
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Assignee:
SMITHKLINE BEECHAM CORP
SMITHKLINE BEECHAM PLC
International Classes:
G01N33/53; A61K38/00; A61K39/395; A61K48/00; A61P1/00; A61P9/00; A61P13/02; A61P15/00; A61P25/00; A61P27/02; A61P43/00; C07K14/31; C07K16/12; C12N5/10; C12N9/12; C12N15/00; C12N15/09; C12P21/02; G01N33/15; C12R1/91; (IPC1-7): C12N15/09; A61K38/00; A61K39/395; A61K48/00; C07K14/31; C07K16/12; C12N5/10; C12N9/12; C12P21/02; G01N33/15; G01N33/53
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)