Title:
ジアゾケトン基を有する固相粒子
Document Type and Number:
Japanese Patent JP4525951
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain a solid-phase particle, capable of producing a carboxylic acid, ketone or oxazole derivative with increased carbon content, and useful for solid-phase synthesis or the like. SOLUTION: This solid-phase particle has a group shown by the formula C(=O)-C(=N2)-Y [Y is H or SiR1SiR2SiR3 (R1 to R3 are each alkyl)]. It is preferable to react a solid-phase particle shown by the formula C(=O)-X (X is a halogen) with a compound shown by the formula R51OH (R51 is H or an organic residue), R52R53NH (R52 and R53 are each R51) or R54SH (R54 is R51), to produce the solid-phase particle having a group shown by the formula CH(Y)- C(=O)-R4 (R4 is OR51, NR52R53 or SR54), or with a compound shown by the formula R6CN (R6 is H or an organic residue) in the presence of a Lewis acid, to produce the solid-phase particle having the group shown above.
Inventors:
Hirohisa Shindo
Yasushi Imune
Yasushi Imune
Application Number:
JP2000023525A
Publication Date:
August 18, 2010
Filing Date:
February 01, 2000
Export Citation:
Assignee:
Shionogi Pharmaceutical Co., Ltd.
International Classes:
C07D263/32; C07B37/04; C07F7/10; C07B41/08; C07B43/04; C07B45/06; C07B61/00; C07C45/67; C07C49/84; C07C51/00; C07C51/09; C07C67/08; C07C67/18; C07C67/333; C07C69/34; C07C69/50; C07C69/732; C07C69/734; C07C69/84; C07C221/00; C07C225/10; C07C231/10; C07C231/12; C07C233/11; C07C235/38; C07C245/14; C07C319/14; C07C319/20; C07C321/28; C07F7/08; C08G65/26
Domestic Patent References:
| JP5764620A |
Other References:
Tetrahedron Letters,1997年,Vol. 38, No. 35,6145-6148
Attorney, Agent or Firm:
Hideaki Yamauchi
Kenichi Sugita
Kenichi Sugita