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Title:
SOLUTION PREPARATION FOR INHALATION THERAPY WITH FORMOTEROL
Document Type and Number:
Japanese Patent JP2005047933
Kind Code:
A
Abstract:

To resolve problems that formoterol has been used only in the form of powder in conventional inhalation therapies, because a formoterol solution can not be stored with enough stable way to assure medicinal quality of a product for a long time, and liquid aerosol products of formoterol have been found to be unsuitable for use of nebulisers for ambulant inhalation therapy.

A solution preparation for inhalation therapy containing the formoterol is prepared to have pH of about 4.5-5.5 and comprises 0.9-1.5 mg/ml of formoterol in an ethanol/water-mixed solvent, a pharmacologically acceptable quantity of preservative and a pharmacologically acceptable quantity of Na-EDTA.


Inventors:
HOCHRAINER DIETER
ZIERENBERG BERND
Application Number:
JP2004000323973
Publication Date:
February 24, 2005
Filing Date:
November 08, 2004
Export Citation:
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Assignee:
BOEHRINGER INGELHEIM PHARMA
International Classes:
A61K9/08; A61K9/00; A61K9/12; A61K9/72; A61K31/00; A61K31/165; A61K31/167; A61K31/56; A61K45/00; A61K47/04; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/24; A61M11/00; A61M11/02; A61P11/06; A61P11/08; A61K47/02; A61K; A61P; (IPC1-7): A61K31/167; A61K9/08; A61K47/10; A61K47/18; A61M11/00; A61M11/02
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Toshio Imajo
Nobuo Ogawa
Murasha Atsuo
Takayoshi Nishijima
Atsushi Hakoda