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Title:
STABLE AQUEOUS TRANSPARENT SOLUTION, ITS PRODUCTION AND POWDERY COMPOSITION
Document Type and Number:
Japanese Patent JP3181392
Kind Code:
B2
Abstract:

PURPOSE: To obtain a stable aqueous transparent solution of lipid and a powdery composition capable of preserving the aqueous transparent solution for a long period of time.
CONSTITUTION: One or more water-soluble compounds selected from neutral lipid, true wax, sterol, sterol ester, phospholipid, sulfolipid, higher alcohol, higher hydrocarbon and fat-soluble vitamin are uniformly added to water with a higher fatty acid and/or an aliphatic amine by applying physical disturbance. Further, the solution is mixed with an excipient and dried to give a powdery composition. By using a small amount of a fatty acid and/or an aliphatic amine, an aqueous transparent solution of stable lipid can be obtained. The method for preparation is extremely simple. The aqueous transparent solution can be stably preserved as a powdery composition (e.g. freeze-dried substance) for a long period of time and has greatly excellent reproducibility from the powder composition.


Inventors:
Seko, Toshihiro
Ogura, Kazuhito
Sugino, Hiroaki
Toyotama, Hideki
Nakayama, Michiyo
Hama, Michio
Tanaka, Mitsunao
Application Number:
JP1992000224718
Publication Date:
July 03, 2001
Filing Date:
July 31, 1992
Export Citation:
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Assignee:
IATRON LAB INC
STANLEY ELECTRIC CO LTD
International Classes:
A61K47/12; A61K8/02; A61K8/03; A61K8/31; A61K8/34; A61K8/36; A61K8/37; A61K8/41; A61K8/97; A61K8/98; A61K31/01; A61K31/045; A61K31/12; A61K31/23; A61K31/355; A61K31/59; A61K47/18; (IPC1-7): A61K47/12; A61K7/00; A61K31/01; A61K47/18
Attorney, Agent or Firm:
森田 憲一