Title:
置換ヒドロキサム酸およびその使用
Document Type and Number:
Japanese Patent JP2012530703
Kind Code:
A
Abstract:
This invention provides compounds of formula (I) wherein R1, R2, G, m, n, p and q have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders.
Inventors:
Blackburn, christopher
Shabari, jeffrey
Gigstad, Kenneth
Suhi
Shabari, jeffrey
Gigstad, Kenneth
Suhi
Application Number:
JP2012516072A
Publication Date:
December 06, 2012
Filing Date:
June 21, 2010
Export Citation:
Assignee:
MILLENNIUM PHARMACEUTICALS, INC.
International Classes:
C07D209/44; A61K31/4035; A61K31/472; A61K31/4725; A61K31/55; A61P7/02; A61P9/00; A61P9/04; A61P9/12; A61P19/02; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00; C07D217/04; C07D217/06; C07D223/16; C07D401/06; C07D401/12; C07D403/06; C07D405/06; C07D409/06; C07D413/06; C07D413/12; C07D413/14; C07D417/04; C07D417/06; C07D417/14
Domestic Patent References:
| JP2010513318A | 2010-04-30 | |||
| JP2011513468A | 2011-04-28 |
Foreign References:
| US20060004041A1 | 2006-01-05 | |||
| WO2005040161A1 | 2005-05-06 | |||
| WO2008076954A2 | 2008-06-26 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita