Title:
SULFONAMIDE MATRIX METALLOPROTEINASE INHIBITOR
Document Type and Number:
Japanese Patent JP2002308859
Kind Code:
A
Abstract:
To provide a compound which is useful for curing cardiopathy, multiple sclerosis, osteoporosis, etc., as a matrix metalloproteinase inhibitor.
A compound represented by the formula [wherein R1 and R2 are each H, an alkyl or a substituted alkyl; R3 and R4 are each H, a halogen or an alkyl; X is OH or NHOH; and V is O, S, SO2, NR5 (wherein R5 contains H or an alkyl) or CH2] or its salt tolerable as a medicine is provided.
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Inventors:
O'BRIEN PATRICK MICHAEL
PATT WILLIAM CHESTER
PICARD JOSEPH ARMAND
SHULER KEVON RAY
SLISKOVIC DRAGO ROBERT
PATT WILLIAM CHESTER
PICARD JOSEPH ARMAND
SHULER KEVON RAY
SLISKOVIC DRAGO ROBERT
Application Number:
JP2002035628A
Publication Date:
October 23, 2002
Filing Date:
February 13, 2002
Export Citation:
Assignee:
WARNER LAMBERT CO
International Classes:
A61K31/427; A61K31/54; A61K31/541; A61P9/04; A61P19/02; A61P29/00; A61P35/00; A61P43/00; C07D279/12; C07D417/12; C07D417/14; (IPC1-7): C07D279/12; A61K31/427; A61K31/54; A61K31/541; A61P9/04; A61P19/02; A61P29/00; A61P35/00; A61P43/00; C07D417/12; C07D417/14
Attorney, Agent or Firm:
Chika Takagi (2 outside)