硫黄置換スルホニルアミノカルボン酸N-アリールアミド、それらの製造、それらの使用、及びそれらを含む医薬製剤

Japanese Patent JP3786579

B2

The present invention relates to compounds of the formula I wherein A 1 , A 2 , R 1 , R 2 , R 3 , X and n are as defined in the claims, which are valuable pharmaceutically active compounds for the therapy and prophylaxis of diseases, for example of cardiovascular diseases such as hypertension, angina pectoris, cardiac insufficiency, thromboses or atherosclerosis. The compounds of the formula I are capable of modulating the body's production of cyclic guanosine monophosphate (cGMP) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of the formula I, to their use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of the formula I.

WO/2004/033419	SULFONAMIDES HAVING ANTIANGIOGENIC AND ANTICANCER ACTIVITY
JPH0791248	[Title of the Invention] A method for producing an alkoxy or aryloxybenzene compound.
WO/2007/117981	SELECTIVE HYDROXAMATE BASED MMP INHIBITORS

Urzla Schindler
Karl Shenafinger
Hartmut Straubel

JP2000559082A

June 14, 2006

June 25, 1999

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Sanofi-Aventis Deutschland Gesellschaft Mitt Beschlenktel Haftung

C07C311/46; A61K31/18; A61K31/275; A61K31/38; A61K31/381; A61K31/40; A61K31/401; A61K31/403; A61K31/404; A61K31/415; A61K31/4166; A61K31/4184; A61K31/42; A61K31/426; A61K31/428; A61K31/435; A61K31/44; A61K31/4402; A61K31/4409; A61K31/4427; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/445; A61K31/4453; A61K31/4462; A61K31/4535; A61K31/454; A61K31/4545; A61K31/4725; A61K31/495; A61K31/496; A61K31/505; A61K31/506; A61K31/5355; A61K31/5375; A61K31/5377; A61K31/54; A61K31/541; A61K31/551; A61P1/16; A61P3/10; A61P7/02; A61P9/00; A61P9/02; A61P9/04; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P15/10; A61P25/28; A61P43/00; C07C311/21; C07C311/51; C07C311/58; C07C317/40; C07C323/41; C07C323/42; C07C323/52; C07C323/60; C07C331/12; C07D207/12; C07D207/16; C07D207/48; C07D209/10; C07D209/14; C07D211/54; C07D211/96; C07D213/42; C07D213/71; C07D213/78; C07D213/80; C07D213/82; C07D215/36; C07D221/20; C07D231/18; C07D231/42; C07D233/42; C07D233/84; C07D235/18; C07D235/28; C07D239/06; C07D239/42; C07D243/08; C07D261/10; C07D261/16; C07D265/30; C07D277/04; C07D277/10; C07D277/20; C07D277/36; C07D277/46; C07D277/54; C07D277/64; C07D295/08; C07D295/22; C07D295/26; C07D333/34; C07D333/38; C07D333/40; C07D333/62; C07D333/70; C07D401/12; C07D409/12; C07D413/12

JP9043786A
JP7056293A
JP5027380A
JP4285955A

Chika Takagi
Kosuke Nishimura
Hiroshi Sugimoto

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