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Title:
SUPPRESSANT FOR LIBERATION OF HISTAMINE
Document Type and Number:
Japanese Patent JP2000136130
Kind Code:
A
Abstract:

To obtain the subject suppressant by including alnusenol and multiflorenol as active ingredients.

This suppressant is obtained by including alnusenol represented by formula I and/or multiflorenol represented by formula II as active ingredients. Furthermore, one or more kinds of isomultiflorenyl acetate represented by formula III, 5-gluten-3β-yl acetate represented by formula IV, spinasterol represented by formula V and ergosterol peroxide represented by formula VI are preferably included. The above active ingredients are obtained as four kinds of triterpenes and two kinds of sterols by defatting a dried material of Benincasa cerifera Savi produced in China with hexane, then extracting the defatted material with methanol under heating, providing a methanol extracted essence, then treating the resultant essence by a column chromatography, removing saccharides and amino acids as a water eluting part, subsequently affording an essence of a methanol eluting part and separating and purifying the resultant essence.


Inventors:
YOSHIZUMI TOMOJI
Application Number:
JP1998000324398
Publication Date:
May 16, 2000
Filing Date:
October 30, 1998
Export Citation:
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Assignee:
CORAL BIOTECH KK
International Classes:
A23L2/52; A23L1/30; A61K31/00; A61K31/045; A61K31/22; A61K31/56; A61K31/575; A61K31/58; A61K36/42; A61P43/00; C07J9/00; C07J63/00; C07J71/00; (IPC1-7): A61K31/045; A23L1/30; A23L2/52; A61K31/22; A61K31/56; A61K31/575; A61K31/58; A61P43/00



 
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