Title:
【発明の名称】チオエ-テルその製法及びこれを含有するアレルギ-性疾病治療剤
Document Type and Number:
Japanese Patent JPH07110848
Kind Code:
B2
Abstract:
Thioethers of the formula I
in which
Ar denotes a phenyl radical, which may optionally be substituted by alkyl, alkenyl, alkoxy, alkylthio, alkanoyl, hydroxyl, hydroxyalkyl, carboxyl, alkoxycarbonyl, carbamoyl, nitro, amino or halogen,
A denotes a straight-chain or branched, saturated or unsaturated C1-C8-alkylene radical, which may optionally be substituted by a hydroxyl group,
n denotes the number 0, 1 or 2,
B denotes a straight-chain or branched, saturated or unsaturated C1-C8-alkylene radical and
R denotes 5-(1H)-tetrazolyl
CN, SCN, OH, halogen, 5-(1H)-tetrazolylthio
where
R1 represents hydrogen, alkyl which may optionally be substituted by cycloalkyl, alkenyl, cycloalkyl, aralkyl and aryl, where the aromatic moiety may be substituted by alkyl, alkenyl, alkoxy, alkylthio, alkanoyl, hydroxyl, hydroxyalkyl, carboxyl, alkoxycarbonyl, carbamoyl, nitro, amino and halogen,
and their pharmacologically tolerable salts are used for controlling allergic diseases.
Inventors:
Erhard Reinholtz
Walter-Gunard Fribe
Wolfgang Campe
Jurgen Melchin
Otto-Henning Willhelms
Walter-Gunard Fribe
Wolfgang Campe
Jurgen Melchin
Otto-Henning Willhelms
Application Number:
JP2193387A
Publication Date:
November 29, 1995
Filing Date:
February 03, 1987
Export Citation:
Assignee:
Beringa-Mannheim Gezershyaft Mitt Besilyen Haftung
International Classes:
A61K31/10; A61K31/135; A61K31/165; A61K31/19; A61K31/235; A61K31/26; A61K31/275; A61K31/41; A61P11/00; A61P29/00; A61P37/08; C07C67/00; C07C313/00; C07C315/02; C07C317/18; C07C317/44; C07C323/12; C07C323/14; C07C323/20; C07C323/52; C07C323/54; C07C323/60; C07C325/00; C07C331/04; C07D257/04; C07D257/06; (IPC1-7): C07C323/12; A61K31/10; A61K31/135; A61K31/165; A61K31/19; A61K31/235; A61K31/26; A61K31/275; A61K31/41; C07C315/02; C07C317/18; C07C317/44; C07C323/14; C07C323/20; C07C323/54; C07C323/60; C07C331/04; C07D257/04; C07D257/06
Attorney, Agent or Firm:
Toshio Yano (1 outside)
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