Title:
【発明の名称】ボロン化されたヌクレオシド
Document Type and Number:
Japanese Patent JPH05507265
Kind Code:
A
Abstract:
A novel class of pharmaceutically active boronated nucleosides are provided. The nucleosides are boronated at a ring nitrogen of the purine or pyrimidine or analogues thereof. Also provided are phosphate esters of these nucleosides and oligomers thereof. Methods of making and using the boronated nucleosides are also disclosed.
Inventors:
Spiel Vogel Bernard F.
Sudo anup
Hall Iris H.
Shaw Barbara Ramsey
Sudo anup
Hall Iris H.
Shaw Barbara Ramsey
Application Number:
JP50522291A
Publication Date:
October 21, 1993
Filing Date:
December 17, 1990
Export Citation:
Assignee:
Boron Biologicals Inc.
DUKE UNIVERSITY
The University of North Carolina at Chapel Hill
DUKE UNIVERSITY
The University of North Carolina at Chapel Hill
International Classes:
A61K31/7135; A61P3/08; A61K31/70; A61P35/00; A61P37/08; C07D473/00; C07D473/18; C07D473/34; C07F5/02; C07H19/04; C07H19/06; C07H19/10; C07H19/16; C07H19/20; C07H21/00; C07H23/00; (IPC1-7): C07H23/00; A61K31/70
Attorney, Agent or Firm:
Shoichi Hase (1 person outside)