Title:
NKT細胞の活性化方法
Document Type and Number:
Japanese Patent JP5005541
Kind Code:
B2
Abstract:
Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from the NKT cell, stimulate proliferation of the NKT cell or upregulate expression of a cell surface marker on the NKT cell. Methods of activating an NKT cell population in a subject are also provided.
Inventors:
Bendelac Albert
Elephant dapen
Tayton Ryuk
Savage pole
Elephant dapen
Tayton Ryuk
Savage pole
Application Number:
JP2007530414A
Publication Date:
August 22, 2012
Filing Date:
September 02, 2005
Export Citation:
Assignee:
The University of Chicago
The Scripts Research Institute
Brigham Young University
The Scripts Research Institute
Brigham Young University
International Classes:
C12N5/0783; A61K31/7028; A61K35/12; A61P31/00; A61P35/00; A61P37/00; C07H15/04
Other References:
Science(2004.12.03),Vol.306,p.1687,1689
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama