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Title:
ハウスダストダニからのアレルゲン蛋白質、ペプチド及びそのための使用
Document Type and Number:
Japanese Patent JP3742426
Kind Code:
B2
Abstract:
Isolated nucleic acids encoding allergens of the species Dermatophagoides pteronyssinus and Dermatophagoides farinae, Der p VII and Der f VII, respectively, are disclosed. A cDNA encoding a peptide having a Der p VII activity and a predicted molecular weight of about 22, 177 daltons is described. A cDNA encoding a peptide having Der f VII activity is also described. The nucleic acids of the invention can be used as probes to detect the presence of Der p VII or Der f VII nucleic acid in a sample or for the recombinant production of peptides having a Der p VII or Der f VII activity. Peptides having a Der p VII or Der f VII activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mite allergens.

Inventors:
Thomas, Wayne Robert
Chua, Coyan
Application Number:
JP51939394A
Publication Date:
February 01, 2006
Filing Date:
March 11, 1994
Export Citation:
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Assignee:
Institute for Child Health Research
International Classes:
C12N15/09; A61K39/00; A61K39/35; A61K39/395; A61P37/08; C07H21/04; C07K14/435; C07K14/47; C07K14/725; C12N1/15; C12N1/19; C12N1/21; C12N5/06; C12N5/10; C12N15/12; C12P21/02; C12P21/06; C12P21/08; C12Q1/02; G01N33/53; G01N33/569; G01N33/68; A61K38/00; A61K38/095
Other References:
Advances in the Biosciences, 1989, Vol.74, p.13-31
Attorney, Agent or Firm:
Motohiro Kurauchi
Hiroshi Kazama