Title:
【発明の名称】ベンゾチオフェン誘導体ならびに対応する使用および組成物
Document Type and Number:
Japanese Patent JP2002511883
Kind Code:
A
Abstract:
The compounds are of the general formula (I): where Z is: -CO-, -CH(OR6)-, -C(NOR7)-; R1 is: H, C1-C6 alkyl, halogen, or - OR12; R2 and R3 are: H, alkyl, halogen, nitro or -OR12, or R2 and R3 together are -C(R8) = C(R9)- C(R10) = C(R11)-; R4 and R5 are: H, alkyl, halogen, haloalkyl, -OR12, nitro, NR13R14; -COR12; CO2R12; -SO2NR13R14; -SO2R12; SR12, cyano; -CONR13R14 or R4 and R5 form a benzene ring; R6 is: H, alkyl, CO2R12, -C(O)NR13R14, naphthyl or phenyl; R7 is: H or alkyl; R8, R9, R10 and R11 are H, alkyl halogen, OR12, nitro, cyano, NR13R14, -COR12, CO2R12; - SO2NR13R14; -SO2R12; SR12, -CONR13R14; R12 is H, C1-C6 alkyl or phenyl; and R13 and R14 are H, alkyl or phenyl or R13 and R14 form a 5- or 6-membered ring. These compounds are effective for the treatment of anxiety or depression.
Inventors:
Monhevega Antonio
Del Rio Zamblana Joaquin
La Cheras Ardas Berta
Palop Cubillo Juan Antonio
Boschlo Villa Anna
Del Castillo Nieto Juan Carlos
Roca Ashin Fan
Del Rio Zamblana Joaquin
La Cheras Ardas Berta
Palop Cubillo Juan Antonio
Boschlo Villa Anna
Del Castillo Nieto Juan Carlos
Roca Ashin Fan
Application Number:
JP50819399A
Publication Date:
April 16, 2002
Filing Date:
July 01, 1998
Export Citation:
Assignee:
Vita-Invest, Es. a.
International Classes:
A61K31/496; A61P25/00; A61P25/22; A61P25/24; C07D333/20; C07D333/22; C07D333/56; C07D333/28; C07D333/32; C07D333/44; C07D333/58; C07D333/64; C07D409/12; (IPC1-7): C07D333/56; A61K31/496; A61P25/00; A61P25/22; A61P25/24; C07D333/58
Attorney, Agent or Firm:
Eiji Saegusa (8 others)