Title:
糖尿病の治療に有用なチオフェン誘導体
Document Type and Number:
Japanese Patent JP2015526416
Kind Code:
A
Abstract:
【課題】糖尿病の治療に有用なチオフェン誘導体の提供。【解決手段】本発明は、以下の一般式Ｉ[化１]のチオフェン誘導体又はそのエナンチオマー、ジアステレオ異性体、水和物、溶媒和物、互変異性体、ラセミ混合物若しくは薬学的に許容される塩に関する。また、糖尿病、その合併症及び／又は関連病状、有利には２型糖尿病又は高血糖の治療及び／又は予防を特に目的とした薬剤としてのそれらの使用に関する。【選択図】なし
Inventors:
Reptile, Frank, F.
Lena, Gelsand, Ale.
Autier, valeri
Kergow, Micheline, Ale.
Fabriel, Laurent, Ale.
Sharon, Christine, Je.
Reinal, Sophie, N.
Ode, Annick, M.
Lena, Gelsand, Ale.
Autier, valeri
Kergow, Micheline, Ale.
Fabriel, Laurent, Ale.
Sharon, Christine, Je.
Reinal, Sophie, N.
Ode, Annick, M.
Application Number:
JP2015522148A
Publication Date:
September 10, 2015
Filing Date:
July 16, 2013
Export Citation:
Assignee:
METABRAIN RESEARCH
International Classes:
C07D333/24; A61K31/155; A61K31/381; A61K31/4025; A61K31/41; A61K31/4245; A61K31/427; A61K31/4436; A61K31/496; A61K31/5377; A61K31/7042; A61P3/10; A61P43/00; C07D333/34; C07D333/38; C07D409/04; C07D409/06; C07D409/12; C07D409/14; C07D417/06; C07H9/02
Domestic Patent References:
| JPH10195070A | 1998-07-28 | |||
| JP2011507910A | 2011-03-10 | |||
| JP2006503111A | 2006-01-26 |
Foreign References:
| WO2002095361A2 | 2002-11-28 | |||
| WO2005081954A2 | 2005-09-09 | |||
| WO2008051197A2 | 2008-05-02 |
Other References:
"Registry No.４９９１８９−６７−２", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000212, 17 May 2003 (2003-05-17), ISSN: 0003486241
"Registry No.４１２９６０−４４−２", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000213, 9 May 2002 (2002-05-09), ISSN: 0003486242
"Registry No.４００８２４−２２−８", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000214, 14 March 2002 (2002-03-14), ISSN: 0003486243
"Registry No.４００８２４−１６−０", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000215, 14 March 2002 (2002-03-14), ISSN: 0003486244
"Registry No.４００８２４−１３−７", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000216, 14 March 2002 (2002-03-14), ISSN: 0003486245
"Registry No.３７１１４０−２３−７", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000217, 20 November 2001 (2001-11-20), ISSN: 0003486246
"Registry No.３００８０１−４０−５", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000218, 2 November 2000 (2000-11-02), ISSN: 0003486247
"Registry No.３００４０６−２３−９", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000219, 30 October 2000 (2000-10-30), ISSN: 0003486248
ＢＩＯＯＲＧＡＮＩＣ ＆ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ＬＥＴＴＥＲＳ, JPN6017002023, 2007, pages 17 - 7, ISSN: 0003486235
ＢＩＯＯＲＧＡＮＩＣ ＆ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ, vol. 14, no. 2, JPN6017002027, 2006, pages 395 - 408, ISSN: 0003486236
PHARMACEUTICAL CHEMISTRY JOURNAL (A TRANSLATION OF KHIMIKO-FARMATSEVTICHESKII ZHURNAL), vol. 21, no. 11, JPN6017002029, 1988, pages 772 - 777, ISSN: 0003486237
"Registry No.６９２２７２−４１−６", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000209, 13 June 2004 (2004-06-13), ISSN: 0003486238
"Registry No.６９２２６７−０５−３", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000210, 13 June 2004 (2004-06-13), ISSN: 0003486239
"Registry No.５５１９２１−９５−０", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000211, 21 July 2003 (2003-07-21), ISSN: 0003486240
"Registry No.４１２９６０−４４−２", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000213, 9 May 2002 (2002-05-09), ISSN: 0003486242
"Registry No.４００８２４−２２−８", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000214, 14 March 2002 (2002-03-14), ISSN: 0003486243
"Registry No.４００８２４−１６−０", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000215, 14 March 2002 (2002-03-14), ISSN: 0003486244
"Registry No.４００８２４−１３−７", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000216, 14 March 2002 (2002-03-14), ISSN: 0003486245
"Registry No.３７１１４０−２３−７", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000217, 20 November 2001 (2001-11-20), ISSN: 0003486246
"Registry No.３００８０１−４０−５", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000218, 2 November 2000 (2000-11-02), ISSN: 0003486247
"Registry No.３００４０６−２３−９", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000219, 30 October 2000 (2000-10-30), ISSN: 0003486248
ＢＩＯＯＲＧＡＮＩＣ ＆ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ ＬＥＴＴＥＲＳ, JPN6017002023, 2007, pages 17 - 7, ISSN: 0003486235
ＢＩＯＯＲＧＡＮＩＣ ＆ ＭＥＤＩＣＩＮＡＬ ＣＨＥＭＩＳＴＲＹ, vol. 14, no. 2, JPN6017002027, 2006, pages 395 - 408, ISSN: 0003486236
PHARMACEUTICAL CHEMISTRY JOURNAL (A TRANSLATION OF KHIMIKO-FARMATSEVTICHESKII ZHURNAL), vol. 21, no. 11, JPN6017002029, 1988, pages 772 - 777, ISSN: 0003486237
"Registry No.６９２２７２−４１−６", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000209, 13 June 2004 (2004-06-13), ISSN: 0003486238
"Registry No.６９２２６７−０５−３", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000210, 13 June 2004 (2004-06-13), ISSN: 0003486239
"Registry No.５５１９２１−９５−０", ＤＡＴＡＢＡＳＥ ＲＥＧＩＳＴＲＹ［ＯＮＬＩＮＥ］ ＲＥＴＲＩＥＶＥＤ ＦＲＯＭ ＳＴＮ, JPN7017000211, 21 July 2003 (2003-07-21), ISSN: 0003486240
Attorney, Agent or Firm:
Atomi International Patent Office