Title:
卵巣癌の早期診断方法
Document Type and Number:
Japanese Patent JP2007503817
Kind Code:
A
Abstract:
The present invention discloses the protease hepsin is specifically over-expressed in ovarian and other malignancies. A number of hepsin peptides can induce immune responses to hepsin, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies. There is also provided a hepsin protein variant that is useful as a marker for ovarian cancer cells, prostate cancer cells or kidney cancer cells.
Inventors:
O'Brien, Timothy
Canon, martin jay
Beard, John
Santin, Alessandro
Kazushige Shigemasa
Canon, martin jay
Beard, John
Santin, Alessandro
Kazushige Shigemasa
Application Number:
JP2006524945A
Publication Date:
March 01, 2007
Filing Date:
August 30, 2004
Export Citation:
Assignee:
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
International Classes:
C12N15/09; A61K35/76; A61K38/48; A61K39/00; A61K39/39; A61K39/395; A61K48/00; A61P35/00; C07K14/435; C12N9/64; C12Q1/02; C12Q1/04; C12Q1/37; C12Q1/68; G01N33/15; G01N33/50; G01N33/573; G01N33/574
Domestic Patent References:
| JP2003523524A | 2003-08-05 | |||
| JP2003512036A | 2003-04-02 |
Foreign References:
| US20030027181A1 | 2003-02-06 |
Attorney, Agent or Firm:
Yanagita Seiji
Go Sakuma
Go Sakuma