Title:
The interferon yield inducer containing lactic acid bacteria
Document Type and Number:
Japanese Patent JP6170190
Kind Code:
B2
Abstract:
This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp. lactis JCM20101, Leuconostoc lactis NBRC12455, Leuconostoc lactis NRIC1540, Pediococcus damnosus JCM5886, or Streptococcus thermophilus TA-45.
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Inventors:
Daisuke Fujiwara
Kenta Jouchi
Satoshi Sugimura
Kenta Jouchi
Satoshi Sugimura
Application Number:
JP2016004279A
Publication Date:
July 26, 2017
Filing Date:
January 13, 2016
Export Citation:
Assignee:
Kirin Holdings Company, Limited
Koiwai Dairy Co., Ltd.
Koiwai Dairy Co., Ltd.
International Classes:
A23L33/135; A23C9/123; A23C19/032; A61K35/744; A61K35/747
Domestic Patent References:
| JP2009296972A |
Foreign References:
| WO2009150897A1 | ||||
| WO2009005123A1 | ||||
| WO2009157073A1 | ||||
| WO2009007515A1 |
Other References:
日本農芸化学会大会講演要旨集,2004年 3月 5日,p.215,3A19p03
Lammers K, et al.,DNA derived from probiotic bacteria modulates human dendritic cell phenotype and function,Gastroenterology,2004年 4月,Vol. 126, No. 4,p. A517 (#T1815)
Toki S, et al.,Gene expression profiles in the plasmacytoid dendritic cells stimulated with Lactobacillus GG or E.c,Journal of Allergy and Clinical Immunology,2007年 1月,Vol. 119, No. 1,p. S259 (#1013)
Kimoto-Nira H, et al.,Anti-ageing effect of a lactococcal strain: analysis using senescence-accelerated mice,British Journal of Nutrition,2007年12月,Vol. 98, No. 6,p. 1178-1186
Enomoto A, et al.,SKGマウスの脾臓細胞のサイトカイン産生応答に及ぼす乳酸菌の効果,日本免疫学会総会・学術集会記録,2008年11月 5日,Vol. 38,p. 174 (2G-W29-11-P)
丸尾俊也, et al.,Lactococcus lactis subsp. cremoris FC 株牛乳発酵物の経口投与がインフルエンザウイルス感染モデルマウス,日本食品科学工学会大会講演集,2010年 9月 1日,Vol. 57th,p. 106 (2Ep8)
Lei H, et al.,Immunoprotection against influenza H5N1 virus by oral administration of enteric-coated recombinant L,Virology,2010年11月25日,Vol. 407, No. 2,p. 319-324
Lammers K, et al.,DNA derived from probiotic bacteria modulates human dendritic cell phenotype and function,Gastroenterology,2004年 4月,Vol. 126, No. 4,p. A517 (#T1815)
Toki S, et al.,Gene expression profiles in the plasmacytoid dendritic cells stimulated with Lactobacillus GG or E.c,Journal of Allergy and Clinical Immunology,2007年 1月,Vol. 119, No. 1,p. S259 (#1013)
Kimoto-Nira H, et al.,Anti-ageing effect of a lactococcal strain: analysis using senescence-accelerated mice,British Journal of Nutrition,2007年12月,Vol. 98, No. 6,p. 1178-1186
Enomoto A, et al.,SKGマウスの脾臓細胞のサイトカイン産生応答に及ぼす乳酸菌の効果,日本免疫学会総会・学術集会記録,2008年11月 5日,Vol. 38,p. 174 (2G-W29-11-P)
丸尾俊也, et al.,Lactococcus lactis subsp. cremoris FC 株牛乳発酵物の経口投与がインフルエンザウイルス感染モデルマウス,日本食品科学工学会大会講演集,2010年 9月 1日,Vol. 57th,p. 106 (2Ep8)
Lei H, et al.,Immunoprotection against influenza H5N1 virus by oral administration of enteric-coated recombinant L,Virology,2010年11月25日,Vol. 407, No. 2,p. 319-324
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Natsuo Tanaka
Satoshi Fujita
Natsuo Tanaka
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