Title:
セピアプテリン及びテトラヒドロラクトイルプテリンの製造法
Document Type and Number:
Japanese Patent JPWO2013168693
Kind Code:
A1
Abstract:
セピアプテリン、ラクトイルプテリン及びテトラヒドロラクトイルプテリンの製造法の提供。以下の反応式により、セピアプテリン、ラクトイルプテリン及びテトラヒドロラクトイルプテリンが収率良く得られる。
Inventors:
Hiroshi Yoshino
Taichi recommenda
Yuichi Castle
Shunichi Murata
Murata Shizuaki
Yasuhiro Kuroda
Taichi recommenda
Yuichi Castle
Shunichi Murata
Murata Shizuaki
Yasuhiro Kuroda
Application Number:
JP2014514717A
Publication Date:
January 07, 2016
Filing Date:
May 07, 2013
Export Citation:
Assignee:
Shiratori Pharmaceutical Co., Ltd.
International Classes:
C07D475/04
Domestic Patent References:
| JPS61172877A | 1986-08-04 |
Foreign References:
| WO2011132435A1 | 2011-10-27 | |||
| WO2005049614A2 | 2005-06-02 |
Other References:
FAN,C.L. ET AL: "Partial purification and some properties of biopterin synthase and dihydropterin oxidase from Drosop", BIOCHEMICAL GENETICS, vol. Vol.17, No.3-4, JPN6013025452, 1979, pages 351 - 369, ISSN: 0003481591
HELVETICA CHIMICA ACTA, vol. 61, no. 7, JPN6017001220, 1978, pages 2731 - 2738, ISSN: 0003481597
LANDGE,S.S. ET AL: "Chemoselective oxidation of 6-hydroxyalkylpteridine and its application to synthesis of 6-acyl-7,8-d", HETEROCYCLES, vol. 71, no. 4, JPN6013037297, 2007, pages 911 - 918, XP008175195, ISSN: 0003481592
CHOI,Y.K. ET AL: "Functional role of sepiapterin reductase in the biosynthesis of tetrahydropteridines in Dictyosteliu", BIOCHIMICA ET BIOPHYSICA ACTA, GENERAL SUBJECTS, vol. 1760, no. 6, JPN6013037298, 2006, pages 877 - 882, XP025015007, ISSN: 0003481593, DOI: 10.1016/j.bbagen.2005.11.017
SATO,N. ET AL: "Studies on pyrazines. 17. An efficient synthesis of pteridine-6-carboxylic acids", JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 25, no. 6, JPN6013037299, 1988, pages 1737 - 1740, XP002049102, ISSN: 0003481594, DOI: 10.1002/jhet.5570250625
PFLEIDERER,W.: "Pteridines. LXVIII. Transformation of biopterin into sepiapterin and absolute configuration of sep", CHEMISCHE BERICHTE, vol. 112, no. 7, JPN6013037300, 1979, pages 2750 - 2755, ISSN: 0003481595
NAIR,M.G. ET AL: "Folate analogs. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-dea", JOURNAL OF MEDICINAL CHEMISTRY, vol. 32, no. 6, JPN6013037302, 1989, pages 1277 - 1283, XP055172502, ISSN: 0003481596, DOI: 10.1021/jm00126a022
HELVETICA CHIMICA ACTA, vol. 61, no. 7, JPN6017001220, 1978, pages 2731 - 2738, ISSN: 0003481597
LANDGE,S.S. ET AL: "Chemoselective oxidation of 6-hydroxyalkylpteridine and its application to synthesis of 6-acyl-7,8-d", HETEROCYCLES, vol. 71, no. 4, JPN6013037297, 2007, pages 911 - 918, XP008175195, ISSN: 0003481592
CHOI,Y.K. ET AL: "Functional role of sepiapterin reductase in the biosynthesis of tetrahydropteridines in Dictyosteliu", BIOCHIMICA ET BIOPHYSICA ACTA, GENERAL SUBJECTS, vol. 1760, no. 6, JPN6013037298, 2006, pages 877 - 882, XP025015007, ISSN: 0003481593, DOI: 10.1016/j.bbagen.2005.11.017
SATO,N. ET AL: "Studies on pyrazines. 17. An efficient synthesis of pteridine-6-carboxylic acids", JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 25, no. 6, JPN6013037299, 1988, pages 1737 - 1740, XP002049102, ISSN: 0003481594, DOI: 10.1002/jhet.5570250625
PFLEIDERER,W.: "Pteridines. LXVIII. Transformation of biopterin into sepiapterin and absolute configuration of sep", CHEMISCHE BERICHTE, vol. 112, no. 7, JPN6013037300, 1979, pages 2750 - 2755, ISSN: 0003481595
NAIR,M.G. ET AL: "Folate analogs. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-dea", JOURNAL OF MEDICINAL CHEMISTRY, vol. 32, no. 6, JPN6013037302, 1989, pages 1277 - 1283, XP055172502, ISSN: 0003481596, DOI: 10.1021/jm00126a022
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto