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Title:
【発明の名称】長期存続抗腫瘍剤の産生のための方法および組成物
Document Type and Number:
Japanese Patent JP2003508502
Kind Code:
A
Abstract:
Derivatives of antineoplastic agents are prepared. The derivatives are capable of forming covalent bonds with one or more blood components, preferably a mobile blood component.

Inventors:
Brydon, Dominick Peep.
Rigger, roger
Fan, shitzai
Milner, Peter G.
Smith, Damon
Ezrin, Alan Em.
Application Number:
JP2001521398A
Publication Date:
March 04, 2003
Filing Date:
September 07, 2000
Export Citation:
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Assignee:
Conjuchem, Incorporated
International Classes:
C07D473/10; A61K9/00; A61K9/12; A61K9/14; A61K31/138; A61K31/192; A61K31/401; A61K31/4015; A61K31/4025; A61K31/407; A61K31/437; A61K31/454; A61K31/4545; A61K31/496; A61K31/519; A61K31/522; A61K38/00; A61K38/22; A61K38/55; A61K47/42; A61K47/48; A61P3/10; A61P5/10; A61P5/14; A61P5/16; A61P5/38; A61P9/00; A61P9/06; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P11/08; A61P25/00; A61P25/04; A61P25/24; A61P29/00; A61P31/00; A61P31/12; A61P31/18; A61P35/00; A61P37/06; A61P37/08; A61P41/00; A61P43/00; C07D207/452; C07D401/12; C07D401/14; C07D405/12; C07D475/08; C07D487/14; C07D519/04; (IPC1-7): A61K31/4025; A61K31/4015; A61K31/407; A61K31/437; A61K31/519; A61P35/00
Domestic Patent References:
JPH09503511A1997-04-08
JP2001500133A2001-01-09
JPH04346918A1992-12-02
JP2001519784A2000-07-17
JPH01211530A1989-08-24
JP2002512640A2002-04-23
JP2003501486A2003-01-14
Foreign References:
WO1998000171A21998-01-08
WO1998013059A11998-04-02
Other References:
BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1118, JPN7009002733, pages 83 - 90, ISSN: 0001336003
J.MED.CHEM., vol. 43, JPN6009026653, pages 1253 - 1256, ISSN: 0001336004
Attorney, Agent or Firm:
Shusaku Yamamoto