Title:
The method and kit for discriminating a benign breast disease from a breast cancer
Document Type and Number:
Japanese Patent JP5932778
Kind Code:
B2
Abstract:
A method and kit for discriminating between breast cancer and benign breast disease by the determination of the expression level of at least one target gene having a nucleic acid sequence selected from the nucleic acid sequences set forth in SEQ ID NOs: 1, 2 or 3, 4 and 5 or 6 to obtain an expression profile for the patient, and the comparison of the expression profile of the patient with expression profiles of target genes from patients previously clinically classified as breast cancer and expression profiles of target genes from patients previously clinically classified as benign breast disease.
Inventors:
Yeah, Shun
Woo, Faye
Shui, Chinghua
Mon, Xia
Brujan, Mougins
Woo, Faye
Shui, Chinghua
Mon, Xia
Brujan, Mougins
Application Number:
JP2013511503A
Publication Date:
June 15, 2016
Filing Date:
May 28, 2010
Export Citation:
Assignee:
BIOMERIEUX
International Classes:
C12Q1/68
Domestic Patent References:
| JP2008506407A | ||||
| JP2011502487A | ||||
| JP2009168514A |
Foreign References:
| WO2009059414A1 | ||||
| WO2009083780A1 | ||||
| WO2009039023A2 | ||||
| WO2007067813A2 | ||||
| US20070015148 |
Other References:
Lancet Oncol.,2009 Apr,10(4),p.381-90,Epub 2009 Feb 25
Br J Cancer.,2010 Feb 2,102(3),p.462-8,Epub 2010 Jan 12
Machine Learning,2002 Jan,46(1),p.389-422
Artif Intell Med.,2005 Sep-Oct,35(1-2),p.185-94
Cancer Res.,2005 Feb 15,65(4),p.1587-97
BARAK,M. et al.,CA-15.3, TPA and MCA as markers for breast cancer.,Eur. J. Cancer,1990年 5月,Vol.26, No.5,pp.577-80
RUNDLE,A. et al.,Association between the ras p21 oncoprotein in blood samples and breast cancer.,Cancer Lett.,2002年11月 8日,Vol.185, No.1,pp.71-8
QIN,W. et al.,Increased expression of the inflammatory protein YKL-40 in precancers of the breast.,Int. J. Cancer,2007年10月 1日,Vol.121, No.7,pp.1536-42
LEANDRO-GARCIA,L.J. et al.,Tumoral and tissue-specific expression of the major human beta-tubulin isotypes.,Cytoskeleton,2010年 4月,Vol.67, No.4,pp.214-23
Br J Cancer.,2010 Feb 2,102(3),p.462-8,Epub 2010 Jan 12
Machine Learning,2002 Jan,46(1),p.389-422
Artif Intell Med.,2005 Sep-Oct,35(1-2),p.185-94
Cancer Res.,2005 Feb 15,65(4),p.1587-97
BARAK,M. et al.,CA-15.3, TPA and MCA as markers for breast cancer.,Eur. J. Cancer,1990年 5月,Vol.26, No.5,pp.577-80
RUNDLE,A. et al.,Association between the ras p21 oncoprotein in blood samples and breast cancer.,Cancer Lett.,2002年11月 8日,Vol.185, No.1,pp.71-8
QIN,W. et al.,Increased expression of the inflammatory protein YKL-40 in precancers of the breast.,Int. J. Cancer,2007年10月 1日,Vol.121, No.7,pp.1536-42
LEANDRO-GARCIA,L.J. et al.,Tumoral and tissue-specific expression of the major human beta-tubulin isotypes.,Cytoskeleton,2010年 4月,Vol.67, No.4,pp.214-23
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori