Title:
【発明の名称】インテグリンアンタゴニストとしての新規なビフェニル及びビフェニル-類似化合物
Document Type and Number:
Japanese Patent JP2002532465
Kind Code:
A
Abstract:
The present invention relates to biphenyl and biphenyl-analogous compounds, their preparation and use as pharmaceutical compositions, as integrin antagonists and in particular for the production of pharmaceutical compositions for the treatment and prophylaxis of cancer, arteriosclerosis, restenosis, osteolytic disorders such as osteoporosis and ophthalmic diseases. The compounds according to the invention have formula (1) wherein R<1>, R<2>, U, V, A, B, W, R<3>, C and R<4> have the meaning as defined in the claims.
Inventors:
Albers, Marx
Urbanus, Claus
Andrea Baupel
Hellter michael
Schmidt, Delf
Schuterte-Ludwig, Beatrix
Gerdes, Christoph
Sichtal, Elke
Kerdenich, Jerck
Briyuge myer, wolf
Le Steig, Clemens
Urbanus, Claus
Andrea Baupel
Hellter michael
Schmidt, Delf
Schuterte-Ludwig, Beatrix
Gerdes, Christoph
Sichtal, Elke
Kerdenich, Jerck
Briyuge myer, wolf
Le Steig, Clemens
Application Number:
JP2000588126A
Publication Date:
October 02, 2002
Filing Date:
December 13, 1999
Export Citation:
Assignee:
Bayer Aktiengesellschaft
International Classes:
A61K31/192; A61K31/27; A61K31/277; A61K31/341; A61K31/381; A61K31/40; A61K31/415; A61K31/417; A61K31/4184; A61K31/42; A61K31/426; A61K31/428; A61K31/433; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/5375; A61P9/10; A61P19/02; A61P19/10; A61P27/02; A61P29/00; A61P35/00; C07C269/06; C07C271/22; C07C273/18; C07C275/42; C07C303/40; C07C311/06; C07C311/10; C07C311/14; C07C311/19; C07C311/37; C07C311/46; C07C311/47; C07C335/20; C07D207/22; C07D213/40; C07D213/55; C07D213/61; C07D213/73; C07D213/74; C07D213/75; C07D213/82; C07D231/18; C07D233/50; C07D233/54; C07D233/64; C07D233/84; C07D295/12; C07D233/88; C07D233/90; C07D235/14; C07D235/30; C07D261/10; C07D261/14; C07D263/58; C07D277/20; C07D277/42; C07D277/46; C07D277/48; C07D277/54; C07D277/82; C07D285/10; C07D285/135; C07D285/14; C07D295/13; C07D295/15; C07D307/14; C07D307/16; C07D307/52; C07D307/68; C07D333/34; C07D333/36; C07D401/12; C07D409/12; C07D413/12; C07D417/12; C07D521/00; C07F5/02; C07D235/10; C07D285/12; (IPC1-7): C07C271/22; A61K31/192; A61K31/27; A61K31/277; A61K31/341; A61K31/381; A61K31/40; A61K31/415; A61K31/417; A61K31/4184; A61K31/42; A61K31/426; A61K31/428; A61K31/433; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/5375; A61P9/10; A61P19/02; A61P19/10; A61P29/00; A61P35/00; C07C269/06; C07C273/18; C07C275/42; C07C303/40; C07C311/06; C07C311/10; C07C311/19; C07D213/40; C07D213/61; C07D213/73; C07D213/74; C07D231/18; C07D233/64; C07D235/30; C07D261/10; C07D277/42; C07D277/46; C07D277/48; C07D277/82; C07D285/10; C07D285/135; C07D295/12; C07D307/16; C07D307/68; C07D333/34; C07F5/02
Attorney, Agent or Firm:
Heiyoshi Odashima