Title:
【発明の名称】4―ベンゾイル―5―ヒドロキシピラゾール類の製法
Document Type and Number:
Japanese Patent JP2699549
Kind Code:
B2
Abstract:
A process for producing a 4-benzoyl-5-hydroxylpyrazole of the formula III: wherein A is an alkyl group having from 1 to 3 carbon atoms, an allyl group or a propargyl group, B is a hydrogen atom or a methyl group, R<1> is an alkyl group having from 1 to 4 carbon atoms, an alkoxy group having from 1 to 4 carbon atoms, a trifluoromethyl group, a nitro group, a cyano group or a halogen atom, R<2> is a hydrogen atom, an alkyl group having from 1 to 4 carbon atoms, an alkoxy group having from 1 to 4 carbon atoms, a hydroxy group, an alkoxyalkoxy group having from 3 to 6 carbon atoms, an alkoxyalkyl group having from 2 to 5 carbon atoms, an alkoxycarbonyl group having from 2 to 5 carbon atoms, a carboxyl group, a nitro group, a cyano group or a halogen atom, and R<3> is an alkylthio group having from 1 or 2 carbon atoms, an alkylsulfinyl group having 1 or 2 carbon atoms, an alkanesulfonyl group having 1 or 2 carbon atoms, a trifluoromethyl group, a nitro group, a cyano group or a halogen atom, which comprises reacting carbon monoxide and a 5-hydroxypyrazole of the formula II: wherein A and B are as defined above, to a substituted benzene of the formula I: wherein X is a bromine atom, an iodine atom or a diazonium tetrafluoroboron salt group, R<1> is as defined above, provided that when X is a bromine atom, R<1> is a fluorine atom or a chlorine atom, and when X is an iodine atom, R<1> is a fluorine atom, a chlorine atom or a bromine atom, R<2> is as defined above, provided that when X is a bromine atom, R<2> is a fluorine atom or a chlorine atom, and when X is an iodine atom, R<2> is a fluorine atom, a chlorine atom or a bromine atom, and R<3> is as defined above, provided that when X is a bromine atom, R<3> is a fluorine atom or a chlorine atom, and when X is an iodine atom, R<3> is a fluorine atom, a chlorine atom or a bromine atom, in the presence of a base and a catalyst of Group VIII of the Periodic Table.
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Inventors:
Norio Tanaka
Kakuda Takuya
Eiichi Oya
Masaki Baba
Kakuda Takuya
Eiichi Oya
Masaki Baba
Application Number:
JP13417289A
Publication Date:
January 19, 1998
Filing Date:
May 26, 1989
Export Citation:
Assignee:
Nissan Chemical Industry Co., Ltd.
International Classes:
A01N43/56; B01J27/128; B01J31/28; C07B61/00; C07C17/12; C07C25/02; C07C25/13; C07C43/174; C07C63/70; C07C205/12; C07C205/19; C07C205/34; C07C245/20; C07C255/50; C07C255/53; C07C255/54; C07C317/14; C07C317/22; C07C317/32; C07C317/44; C07C317/46; C07D231/20; C07C323/09; C07C323/20; C07C323/36; C07C323/48; C07C323/62; C07C323/63; C07C331/12; C07D231/22; (IPC1-7): C07D231/20; A01N43/56; C07C17/12; C07C25/13; C07C43/174; C07C63/70; C07C245/20; C07C255/50; C07C255/53; C07C255/54; C07C317/14; C07C317/22; C07C317/32; C07C317/46; C07C323/09; C07C323/20; C07C323/48; C07C323/62