Title:
【発明の名称】物質の状態調整法
Document Type and Number:
Japanese Patent JPH09501930
Kind Code:
A
Abstract:
PCT No. PCT/SE94/00780 Sec. 371 Date Jan. 30, 1995 Sec. 102(e) Date Jan. 30, 1995 PCT Filed Aug. 25, 1994 PCT Pub. No. WO95/05805 PCT Pub. Date Mar. 2, 1995The present invention relates to a process for providing a stable crystallinic form to a fine-grained substance or a substance mixture, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation of such a substance or a substance mixture, by a) in case of a substance mixture, preparing a homogenous mixture of the substances; b) micronizing, direct precipitating or diminishing by any conventional method the substance or substance mixture into a particle size required for inhalation, the particle size being less than 10 mu m; c) optionally preparing a homogenous mixture of the desired substances when each substance has been introduced from stage b) as separate fine-grained particles; d) conditioning said substance or substance mixture by treatment with a water containing vapor phase in a controlled fashion; and e) drying.
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Inventors:
TROFAST EVA ANN-CHRISTIN (SE)
BRIGGNER LARS-ERIK (SE)
BRIGGNER LARS-ERIK (SE)
Application Number:
JP50751695A
Publication Date:
February 25, 1997
Filing Date:
August 25, 1994
Export Citation:
Assignee:
ASTRA AB (SE)
International Classes:
A61K9/00; A61K9/14; A61K9/72; A61K31/137; A61K31/41; A61K31/4245; A61K31/425; A61K31/426; A61K31/433; A61K31/44; A61K31/496; A61K31/505; A61K47/12; A61P29/00; A61P43/00; B01J2/28; C07C45/68; C07C49/753; C07C65/40; C07C69/94; C07C205/45; C07C225/22; C07C233/33; C07C255/56; C07C311/08; C07D213/28; C07D213/30; C07D213/38; C07D213/40; C07D239/42; C07D271/06; C07D271/10; C07D277/24; C07D285/12; C07D333/38; C07D413/04; (IPC1-7): A61K9/14; B01J2/28; A61K9/72
Attorney, Agent or Firm:
Chika Takagi (2 outside)