Title:
11-O-MOGROL OXIME ETHER DERIVATIVE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/244051
Kind Code:
A1
Abstract:
The present invention provides an 11-O-mogrol oxime ether derivative and a preparation method therefor. The structural formula is as shown in formula (I). The mogrol oxime ether derivative is a product 11-O-mogrol oxime ether derivative obtained by etherifying 11-O-mogrol after oximation of a ketone group thereof. The 11-O-mogrol oxime ether derivative provided in the present invention is simple in terms of preparation method, and has high purity and high yield. Compared with 11-O-mogrol, the obtained 11-O-mogrol oxime ether derivative has significantly enhanced antioxidant activity, water solubility and half-life in vivo, has no toxicity, and can be used as an antioxidant functional additive in oral products such as food, drink, healthcare product and medicine.
Inventors:
LI WEI (CN)
HUANG HUAXUE (CN)
HUANG JUN (CN)
HE JINJUN (CN)
SONG GULIANG (CN)
HUANG HUAXUE (CN)
HUANG JUN (CN)
HE JINJUN (CN)
SONG GULIANG (CN)
Application Number:
PCT/CN2021/074164
Publication Date:
December 09, 2021
Filing Date:
January 28, 2021
Export Citation:
Assignee:
HUNAN HUACHENG BIOTECH INC (CN)
International Classes:
C07J9/00; A23L2/52; A23L33/105; A61K31/575; A61P39/06
Domestic Patent References:
| WO2017075257A2 | 2017-05-04 |
Foreign References:
| CN111560044A | 2020-08-21 | |||
| CN110585053A | 2019-12-20 | |||
| CN105832748A | 2016-08-10 |
Attorney, Agent or Firm:
BEIJING ZHONGZHI XINGYUAN IP LAW FIRM (CN)
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