Title:
2-[1H]-QUINOLONE AND 2-[1H]-QUINOXALONE INHIBITORS OF FACTOR Xa
Document Type and Number:
WIPO Patent Application WO2001057021
Kind Code:
A3
Abstract:
Novel compounds of general formula I, including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivative having activity against mammalian factor Xa is described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis.
Inventors:
ZHU BING-YAN (US)
SCARBOROUGH ROBERT (US)
SCARBOROUGH ROBERT (US)
Application Number:
PCT/US2001/003176
Publication Date:
February 14, 2002
Filing Date:
February 01, 2001
Export Citation:
Assignee:
COR THERAPEUTICS INC (US)
ZHU BING YAN (US)
SCARBOROUGH ROBERT (US)
ZHU BING YAN (US)
SCARBOROUGH ROBERT (US)
International Classes:
A61P7/02; A61P9/02; C07D241/44; C07D401/12; C07D401/14; (IPC1-7): C07D241/44; C07D401/12; C07D401/14; A61K31/497; A61P9/02
Domestic Patent References:
| WO1999050254A1 | 1999-10-07 |
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