4-AMINOPYRIMIDINE DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE DISORDERS

Title:

4-AMINOPYRIMIDINE DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE DISORDERS

Document Type and Number:

WIPO Patent Application WO2005035507

Kind Code:

A3

Abstract:

Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R², G, G', and G" represent substituent groups and R^2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.

Inventors:

DIXON JULIE A (US)
NAGARATHNAM DHANAPALAN (US)
ZHANG LEI (US)
WANG CHUNGUANG (US)
YI LIN (US)
CHEN YUANWEI (US)
CHEN JIANQING (US)
BEAR BRIAN (US)
BRANDS MICHAEL (DE)
HILLISCH ALEXANDER (DE)
BIERER DONALD (US)
WANG MING (US)
FU WENLANG (US)
HENTEMANN MARTIN F (US)
BULLION ANN-MARIE (US)

Application Number:

PCT/US2004/033430

Publication Date:

August 31, 2006

Filing Date:

October 08, 2004

Export Citation:

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Assignee:

BAYER PHARMACEUTICALS CORP (US)
DIXON JULIE A (US)
NAGARATHNAM DHANAPALAN (US)
ZHANG LEI (US)
WANG CHUNGUANG (US)
YI LIN (US)
CHEN YUANWEI (US)
CHEN JIANQING (US)
BEAR BRIAN (US)
BRANDS MICHAEL (DE)
HILLISCH ALEXANDER (DE)
BIERER DONALD (US)
WANG MING (US)
FU WENLANG (US)
HENTEMANN MARTIN F (US)
BULLION ANN-MARIE (US)

International Classes:

C07D401/12; A61K31/506; A61K31/5377; A61P35/00; C07D239/48; C07D401/14; C07D403/12; C07D405/14; C07D409/14; C07D413/14; C07D453/02

Domestic Patent References:

WO2003062225A1	2003-07-31
WO2003062227A1	2003-07-31
WO2004048365A1	2004-06-10

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