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Patent Searching and Data


Title:
ACETYL-COA CARBOXYLASE2 ANTISENSE OLIGONUCLEOTIDES
Document Type and Number:
WIPO Patent Application WO/2020/036353
Kind Code:
A1
Abstract:
The present invention provides the peptide nucleic acid derivative which targets 5' splice site of the human ACC2 pre-mRNA "exon 12". The peptide nucleic acid derivatives in the present invention strongly induce splice variants of the human ACC2 mRNA in cell and are very useful to treat conditions or disorders of skin aging associated with the human ACC2 protein.

Inventors:
HAN SEON-YOUNG (KR)
SUNG KIHO (KR)
HONG MYUNGHYO (KR)
KANG DAYOUNG (KR)
HEO JEONG-SEOK (KR)
JANG KANG WON (KR)
Application Number:
PCT/KR2019/009697
Publication Date:
February 20, 2020
Filing Date:
August 05, 2019
Export Citation:
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Assignee:
OLIPASS CORP (KR)
International Classes:
C07K14/00; A61K8/64; A61K38/00; A61P17/00; A61Q19/08; C12N15/113
Domestic Patent References:
WO2018029517A12018-02-15
WO2018127733A12018-07-12
WO2006110775A22006-10-19
Foreign References:
US20170340544A12017-11-30
KR20120073536A2012-07-05
Other References:
See also references of EP 3837274A4
Attorney, Agent or Firm:
SUH, Jong Wan (KR)
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