Title:
ADENOSINE A3 RECEPTOR AGONISTS
Document Type and Number:
WIPO Patent Application WO2004022573
Kind Code:
A3
Abstract:
Disclosed are novel adenosine A3 receptor agonists, useful for treating various disease states, including neurological and cardiac ischemia, asthma, leukopenia and neutropenia, cancer and inflammation.
Inventors:
CRISTALLI GLORIA
Application Number:
PCT/US2003/028025
Publication Date:
April 08, 2004
Filing Date:
September 08, 2003
Export Citation:
Assignee:
CV THERAPEUTICS INC (US)
International Classes:
A61K31/70; A61K31/7076; A61P25/00; C07H19/16; C07H19/167; (IPC1-7): C07H19/16; A61K31/7076; A61P25/00
Other References:
KLOTZ K-N ET AL: "2-SUBSTITUTED N-ETHYLCARBOXAMIDOADENOSINE DERIVATIVES AS HIGH-AFFINITY AGONISTS AT HUMAN A3 ADENOSINE RECEPTORS", NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY, SPRINGER, BERLIN, DE, vol. 360, no. 2, 1999, pages 103 - 108, XP000984051, ISSN: 0028-1298
BARALDI P G ET AL: "NOVEL N6-(SUBSTITUTED-PHENYLCARBAMOYL)ADENOSINE-5'-URONAMIDES AS POTENT AGONIST FOR A3 ADENOSINE RECEPTORS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 39, no. 3, February 1996 (1996-02-01), pages 802 - 806, XP002913657, ISSN: 0022-2623
BARALDI P G ET AL: "NOVEL N6-(SUBSTITUTED-PHENYLCARBAMOYL)ADENOSINE-5'-URONAMIDES AS POTENT AGONIST FOR A3 ADENOSINE RECEPTORS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 39, no. 3, February 1996 (1996-02-01), pages 802 - 806, XP002913657, ISSN: 0022-2623
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