Title:
AGENT FOR GENERATING HEAT OR SINGLET OXYGEN AND COMPOSITION FOR CANCER TREATMENT EACH COMPRISING ORGANIC PEROXIDE OR CHEMILUMINESCENT COMPOUND
Document Type and Number:
WIPO Patent Application WO/2005/095356
Kind Code:
A1
Abstract:
An agent for heat generation or singlet oxygen generation which, unlike anticancer agents of the alkylating agent type such as MMC, destroys cancer cells by the action of heat and/or singlet oxygen and is effective as a new cancer remedy alleviating the burden to be imposed on the patient. The heat and/or singlet oxygen generator or cancer remedy comprises an organic peroxide, e.g., a peroxide of an imidazole derivative, or a chemiluminescnet compound, e.g., a dioxcetane compound.
Inventors:
KIMURA MASARU
IWAGAKI HIROMI
TSUNENAGA MITSURU
INOUE SHINSUKE
IWAGAKI HIROMI
TSUNENAGA MITSURU
INOUE SHINSUKE
Application Number:
PCT/JP2005/006017
Publication Date:
October 13, 2005
Filing Date:
March 30, 2005
Export Citation:
Assignee:
MANAC INC (JP)
KIMURA MASARU
IWAGAKI HIROMI
TSUNENAGA MITSURU
INOUE SHINSUKE
KIMURA MASARU
IWAGAKI HIROMI
TSUNENAGA MITSURU
INOUE SHINSUKE
International Classes:
A61K31/357; A61K31/416; A61K31/4178; A61K45/00; A61K49/00; A61P35/00; A61P43/00; C07D233/54; C07D233/70; C07D305/14; C07D405/14; (IPC1-7): C07D233/70; A61K31/357; A61K31/416; A61K31/4178; A61K45/00; A61P35/00; A61P43/00; C07D305/14; C07D405/14
Foreign References:
| US5952311A | 1999-09-14 | |||
| US5786198A | 1998-07-28 | |||
| US6160024A | 2000-12-12 | |||
| JPH04279569A | 1992-10-05 | |||
| JPS6314788A | 1988-01-21 | |||
| JPH05117241A | 1993-05-14 |
Other References:
TSUNENAGA M. ET AL.: "Effect of conformational change on chemiluminescence efficiency of 2-(2-hydroxyphenyl)-4,5-diphenylimidazole possessing chelating ability.", ITE LETTERS ON BATTERIES, NEW TEHNOLOGIES & MEDICINE., vol. 4, no. 5, 2003, pages 633 - 638, XP002990125
KIMURA M. ET AL.: "Effect of conformational change on chemilimunescence efficiency of 2-(Ar)-4,5-diphenyl-4H-hydroperoxy-H-imidazole:a new potential signaling system.", ITE LETTERS ON BATTERIES, NEW TECHNOLOGIES & MEDICINE., vol. 1, no. 3, 2000, pages 418 - 421, XP002990126
KIMURA M. ET AL.: "Effect of conformational change on chemilimunescence efficiency of 2-(Ar)-4,5-diphenyl-4H-hydroperoxy-H-imidazole:a new potential signaling system.", ITE LETTERS ON BATTERIES, NEW TECHNOLOGIES & MEDICINE., vol. 1, no. 3, 2000, pages 418 - 421, XP002990126
Attorney, Agent or Firm:
Tsukuni, Hajime (22-12 Toranomon 1-chome, Minato-k, 01 Tokyo, JP)
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