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Title:
AGENT FOR HYPODERMIC INJECTION
Document Type and Number:
WIPO Patent Application WO/2016/092928
Kind Code:
A1
Abstract:
[Problem] To provide an agent for hypodermic injection that has excellent flow characteristics, can, in particular, be used even in thin needles such as needles having an internal diameter of no more than 0.20 mm, and is unlikely to cause pain during injections or inflammation. [Solution] An agent for hypodermic injection, characterized by: having hydrogel containing sintered hydroxyapatite particles; the sintered hydroxyapatite particle content being 1%-60% by mass, relative to the total mass of the agent; and the average diameter of the sintered hydroxyapatite particles being no more than 15 µm.

Inventors:
KANAUCHI ATSUSHI (JP)
Application Number:
PCT/JP2015/076068
Publication Date:
June 16, 2016
Filing Date:
September 14, 2015
Export Citation:
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Assignee:
GENE MEDICAL CO LTD (JP)
International Classes:
A61K33/42; A61K9/08; A61K47/38; A61L27/00; A61P17/00; A61P43/00
Domestic Patent References:
WO2010137122A12010-12-02
WO2005082405A12005-09-09
Foreign References:
JP2013526545A2013-06-24
JP2007537249A2007-12-20
JPH05186364A1993-07-27
JP2012508744A2012-04-12
JP2003507351A2003-02-25
JP2007001865A2007-01-11
JP5774189B12015-09-09
JP5797864B12015-10-21
Other References:
THIOLY-BENSOUSSAN, D.: "Non-hyaluronic acid fillers", CLINICS IN DERMATOLOGY, vol. 26, no. 2, 2008, pages 160 - 176, XP022647616, DOI: doi:10.1016/j.clindermatol.2007.09.017
JI, D. Y. ET AL.: "A novel injectable chitosan/polyglutamate polyelectrolyte complex hydrogel with hydroxyapatite for soft-tissue augmentation", CARBOHYDRATE POLYMERS, vol. 89, no. 4, 2012, pages 1123 - 1130, XP028512034, DOI: doi:10.1016/j.carbpol.2012.03.083
See also references of EP 3231433A4
Attorney, Agent or Firm:
ITOH, ATSUSHI (JP)
Atsushi Ito (JP)
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