Title:
ALKALINE PROTEASE VARIANTS AND DETERGENTS AND CLEANING AGENTS CONTAINING SAID ALKALINE PROTEASE VARIANTS
Document Type and Number:
WIPO Patent Application WO2002088340
Kind Code:
A3
Abstract:
The invention relates to novel alkaline protease variants, which are derived from natural or modified subtilisin proteases. According to the enumeration of the subtilisin from Bacillus lentus, said variants have in relation to the previously known subtilisins the two amino acid positions 199l and 211G and at least one modification preferably after point mutation, which contributes to the stabilisation of the molecule, having the amino acids threonine in position 3 and/or isoleucine in position 4. The variant B. lentus; alkaline protease S3T/V4I/V199I/L211G is examined as an example. In contrast to other protease variants, said variants are characterised by an improved contribution to the cleaning efficiency of detergents and cleaning agents. In addition to these enzymes, the invention relates to their use in diverse technical processes and in particular to detergents and cleaning agents containing said novel alkaline protease variants.
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Inventors:
KOTTWITZ BEATRIX (DE)
MAURER KARL-HEINZ (DE)
BREVES ROLAND (DE)
MAURER KARL-HEINZ (DE)
BREVES ROLAND (DE)
Application Number:
PCT/EP2002/004489
Publication Date:
March 20, 2003
Filing Date:
April 24, 2002
Export Citation:
Assignee:
HENKEL KGAA (DE)
KOTTWITZ BEATRIX (DE)
MAURER KARL-HEINZ (DE)
BREVES ROLAND (DE)
KOTTWITZ BEATRIX (DE)
MAURER KARL-HEINZ (DE)
BREVES ROLAND (DE)
International Classes:
A23C19/032; A23L1/00; A61K8/00; A61K8/64; A61K8/66; A61K8/96; A61Q5/02; A23K1/165; A61Q19/10; C11D3/386; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/54; C12N15/09; C12N15/31; C12N15/57; C12P21/06; C12S7/00; C12S9/00; C12S11/00; G03C11/24; C12R1/07; (IPC1-7): C12N9/54; C12N15/31; C12N5/10; C11D9/40; C11D3/386; C12S9/00; C12S11/00
Domestic Patent References:
| WO1995023221A1 | 1995-08-31 | |||
| WO1989006279A1 | 1989-07-13 |
Foreign References:
| EP0283075A2 | 1988-09-21 |
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