Title:
AMINOCOUMARIN COMPOUND, AND AMINOCOUMARIN COMPOUND-CONTAINING RESIN PARTICLES
Document Type and Number:
WIPO Patent Application WO/2018/151072
Kind Code:
A1
Abstract:
The present invention provides: an aminocoumarin compound having a structure represented by formula (1); and aminocoumarin compound-containing resin particles which include the aminocoumarin compound, and resin particles containing the aminocoumarin compound. In formula (1): each R independently represents hydrogen or a methyl group; Q represents sulfur, oxygen, or N-R1; and R1 represents hydrogen or a methyl group. This aminocoumarin compound is a fluorescent dye which has a longer excitation wavelength than sulfonated coumarin compounds well known in the prior art, and is effectively excited at wavelengths equal to or longer than 475 nm, particularly wavelengths in the vicinity of 500 nm. This aminocoumarin compound is a fluorescent dye which has wavelength characteristics that can be used to perform excitation at wavelengths in the range of 475-510 nm, and enable observation in the green light emission region of 510-540 nm. It is anticipated that the aminocoumarin compound will be suitably utilized in immunostaining or the like.
Inventors:
TAKANASHI KENSAKU (JP)
NAKAYAMA SHIN (JP)
NISHIKAWA KENJI (JP)
ISODA TAKESHI (JP)
NAKAYAMA SHIN (JP)
NISHIKAWA KENJI (JP)
ISODA TAKESHI (JP)
Application Number:
PCT/JP2018/004803
Publication Date:
August 23, 2018
Filing Date:
February 13, 2018
Export Citation:
Assignee:
KONICA MINOLTA INC (JP)
International Classes:
C09B57/02; C09K11/06; G01N33/533
Domestic Patent References:
| WO2015041157A1 | 2015-03-26 |
Foreign References:
| JPH069892A | 1994-01-18 | |||
| JP2006045314A | 2006-02-16 | |||
| JPH06271599A | 1994-09-27 | |||
| JP2004309458A | 2004-11-04 | |||
| JPH07508309A | 1995-09-14 | |||
| JP2015108572A | 2015-06-11 | |||
| JP2014044419A | 2014-03-13 | |||
| JP2013147605A | 2013-08-01 | |||
| JP2013227552A | 2013-11-07 | |||
| JP2013231165A | 2013-11-14 | |||
| JPH08259832A | 1996-10-08 | |||
| JPS466225A | ||||
| JPS51526A | 1976-01-06 | |||
| JPS5069380A | 1975-06-10 | |||
| JPH06271599A | 1994-09-27 |
Other References:
GOOSSENS, KAREL ET AL.: "Accurate Diffusion Coefficients of Organosoluble Reference Dyes in Organic Media Measured by Dual-Focus Fluorescence Correlation Spectroscopy", ACS NANO, vol. 9, no. 7, 2015, pages 7360 - 7373, XP055535817
JUNG, HYO SUNG ET AL.: "Rationally Designed Fluorescence Turn-On Sensors: A New Design Strategy Based on Orbital Control", INORGANIC CHEMISTRY, vol. 49, no. 18, 20 September 2010 (2010-09-20), pages 8552 - 8557, XP055535829
KOMATSU, KENSUKE ET AL.: "Development of an Iminocoumarin-Based Zinc Sensor Suitable for Ratiometric Fluorescence Imaging of Neuronal Zinc", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, no. 44, November 2007 (2007-11-01), pages 13447 - 13454, XP055535833
See also references of EP 3553136A4
JUNG, HYO SUNG ET AL.: "Rationally Designed Fluorescence Turn-On Sensors: A New Design Strategy Based on Orbital Control", INORGANIC CHEMISTRY, vol. 49, no. 18, 20 September 2010 (2010-09-20), pages 8552 - 8557, XP055535829
KOMATSU, KENSUKE ET AL.: "Development of an Iminocoumarin-Based Zinc Sensor Suitable for Ratiometric Fluorescence Imaging of Neuronal Zinc", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, no. 44, November 2007 (2007-11-01), pages 13447 - 13454, XP055535833
See also references of EP 3553136A4
Attorney, Agent or Firm:
SSINPAT PATENT FIRM (JP)
Download PDF: