AMINOETHANOL DERIVATIVES - TAKEDA CHEMICAL INDUSTRIES LTD

Title:

AMINOETHANOL DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/2002/059077

Kind Code:

A1

Abstract:

It is intended to provide drugs which have cholesteryl ester transfer protein inhibitory effect and are useful as blood lipid lowering agent, etc. Namely, compounds represented by the following general formula (I), salts thereof, and medicinal compositions containing the compounds of the formula (I), salts thereof or prodrugs of the same: wherein Ar?1¿ represents an optionally substituted aromatic ring group; Ar?2¿ represents a substituted aromatic ring group; OR'' represents optionally blocked hydroxy; R represents acyl; and R' represents hydrogen or optionally substituted hydrocarbyl.

Inventors:

KORI MASAKUNI (JP)
HAMAMURA KAZUMASA (JP)
FUSE HIROMITSU (JP)
YAMAMOTO TOSHIHIRO (JP)

Application Number:

PCT/JP2002/000532

Publication Date:

August 01, 2002

Filing Date:

January 25, 2002

Export Citation:

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Assignee:

TAKEDA CHEMICAL INDUSTRIES LTD (JP)
KORI MASAKUNI (JP)
HAMAMURA KAZUMASA (JP)
FUSE HIROMITSU (JP)
YAMAMOTO TOSHIHIRO (JP)

International Classes:

A61K31/16; A61K31/166; A61K31/194; A61K31/198; A61K31/22; A61K31/275; A61K31/341; A61K31/343; A61K31/351; A61K31/357; A61K31/36; A61K31/381; A61K31/404; A61K31/42; A61K31/426; A61K31/428; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/47; C07C233/18; C07C233/20; C07C233/60; C07C233/73; C07C235/48; C07C237/30; C07C255/57; C07C271/16; C07C271/22; C07C275/28; C07C275/30; C07C311/19; C07C317/32; C07C323/32; C07C323/60; C07D213/61; C07D277/28; C07D295/192; (IPC1-7): C07C233/18; C07C233/60; C07C233/73; C07C231/02; C07D213/61; C07D319/20; C07D333/24; C07D333/40; C07D213/82; C07D309/38; C07D309/10; C07D333/68; C07D215/50; C07D317/68; C07D307/68; C07D307/79; C07D307/16; C07D339/06; C07D209/42; C07D321/10; C07D307/52; C07D317/46; C07D277/62; C07D277/28; C07D333/28; C07D213/38; C07D213/64; C07D213/65; C07D333/20; C07D261/12; C07D295/12; A61K31/166; A61K31/44; A61K31/357; A61K31/381; A61K31/16; A61K31/4406; A61K31/351; A61K31/36; A61K31/341; A61K31/343; A61K31/275; A61K31/47; A61K31/404; A61K31/428; A61K31/426; A61K31/4409; A61K31/4402; A61K31/42; A61K31/4453; A61K31/22; A61K31/194; A61K31/198; A61P43/00; A61P3/06; A61P9/10; A61P9/08; C07D295/18; C07D295/14

Domestic Patent References:

WO1998035937A1

1998-08-20

Foreign References:

JP2001131137A	2001-05-15
JPH11286478A	1999-10-19
EP0992496A1	2000-04-12

Other References: