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Patent Searching and Data


Title:
ANALOGUES OF GLYCOLIPIDS USEFUL AS IMMUNOADJUVANTS
Document Type and Number:
WIPO Patent Application WO/2009/060305
Kind Code:
A3
Abstract:
The invention provides analogs of alpha-galactosyl ceramide that increase the immune response elicited by various antigens. It also provides methods of using such compounds to increase the effectiveness of vaccines.

Inventors:
PANZA LUIGI (IT)
Application Number:
PCT/IB2008/003263
Publication Date:
May 23, 2013
Filing Date:
October 10, 2008
Export Citation:
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Assignee:
PANZA LUIGI (IT)
International Classes:
C07H15/10; C07H15/18; C07H15/26; A61K39/39
Domestic Patent References:
WO2006026389A22006-03-09
Foreign References:
US20070238871A12007-10-11
EP1776963A12007-04-25
Other References:
WU D ET AL: "Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 103, no. 11, 14 March 2006 (2006-03-14), pages 3972 - 3977, XP008122067, ISSN: 0027-8424, [retrieved on 20030306], DOI: 10.1073/PNAS.0600285103
FUJIO MASAKAZU ET AL: "Structure-Based Discovery of Glycolipids for CD1d-Mediated NKT Cell Activation: Tuning the Adjuvant versus Immunosuppression Activity", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ACS PUBLICATIONS, US, vol. 128, no. 28, 1 January 2006 (2006-01-01), pages 9022 - 9023, XP002493234, ISSN: 0002-7863, DOI: 10.1021/JA062740Z
Attorney, Agent or Firm:
MARSHALL, Cameron, John (43-45 Bloomsbury Square, London WC1A 2RA, GB)
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