Title:
ANTI-OX40 ANTIBODY AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/063162
Kind Code:
A1
Abstract:
The present invention provides an anti-OX40 human antibody. Specifically, a specifically-bound OX40 human antibody is obtained by means of screening with a yeast display technology, and the affinity of the antibody is improved by means of affinity maturation. The present invention also provides application of the antibody to prevention or curing of tumors.
Inventors:
XU TING (CN)
LUAN YAN (CN)
WANG XIAOXIAO (CN)
PENG JIANJIAN (CN)
MA SHULI (CN)
MA HUI (CN)
PAN XIAOLONG (CN)
FU SHILONG (CN)
NING SHANSHAN (CN)
FEI YEQIONG (CN)
ZHAO MENG (CN)
LUAN YAN (CN)
WANG XIAOXIAO (CN)
PENG JIANJIAN (CN)
MA SHULI (CN)
MA HUI (CN)
PAN XIAOLONG (CN)
FU SHILONG (CN)
NING SHANSHAN (CN)
FEI YEQIONG (CN)
ZHAO MENG (CN)
Application Number:
PCT/CN2015/091958
Publication Date:
April 20, 2017
Filing Date:
October 15, 2015
Export Citation:
Assignee:
DINGFU BIOTARGET CO LTD (CN)
International Classes:
C07K16/28; A61K39/395; A61P35/00; C12N15/13; C12N15/63
Foreign References:
| CN104080809A | 2014-10-01 | |||
| CN103717263A | 2014-04-09 |
Other References:
See also references of EP 3363816A4
Attorney, Agent or Firm:
SHNGHAI DIANSHI PARTNERS, P.C. (CN)
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