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Title:
ANTIBODY CAPABLE OF BINDING TO NOVEL CORONAVIRUS (SARS-COV-2) AND SARS CORONAVIRUS (SARS-COV)
Document Type and Number:
WIPO Patent Application WO/2023/002944
Kind Code:
A1
Abstract:
[Problem] The present invention addresses the problem of providing a novel antibody that can prevent and/or treat SARS or COVID-19 infection. Provided is an antibody which comprises heavy-chain CDR1 comprising the amino acid sequence represented by SEQ ID NO:1, heavy-chain CDR2 comprising the amino acid sequence represented by SEQ ID NO:2, heavy-chain CDR3 comprising the amino acid sequence represented by SEQ ID NO:3, light-chain CDR1 comprising the amino acid sequence represented by SEQ ID NO:4, light-chain CDR2 comprising the amino acid sequence represented by SEQ ID NO:5, and light-chain CDR3 comprising the amino acid sequence represented by SEQ ID NO:6 and which is capable of binding to a receptor binding domain (RBD) of S1 subunit of SARS-CoV or SARS-CoV-2, or an antibody fragment of the antibody.

Inventors:
WATANABE SHINYA (JP)
IMAI JUNICHI (JP)
SHIGA HATSUKI (JP)
SATO SHIGEKO (JP)
MATSUKURA SUSUMU (JP)
HOSHI HIROTAKA (JP)
Application Number:
PCT/JP2022/027860
Publication Date:
January 26, 2023
Filing Date:
July 15, 2022
Export Citation:
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Assignee:
PUBLIC UNIV CORPORATION FUKUSHIMA MEDICAL UNIV (JP)
MEDICROME INC (JP)
FUKUSHIMA CELL FACTORY INC (JP)
International Classes:
C07K16/10; A23L33/18; A41D13/11; A61K8/64; A61K9/12; A61K39/395; A61K49/00; A61P31/14; A62B18/02; C07K16/46; C07K17/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12N15/63; C12P21/08
Domestic Patent References:
WO2021045836A12021-03-11
Foreign References:
KR102229225B12021-03-19
KR102205028B12021-01-20
CN111592594A2020-08-28
Attorney, Agent or Firm:
MUTSUKI PARTNERS (JP)
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