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Patent Searching and Data


Title:
ANTICANCER COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2018/193476
Kind Code:
A3
Abstract:
The present invention discloses compounds for inhibition of uncontrolled cell proliferation particularly in cancer stem cells. Particularly, the invention relates to compounds of Formula III to XIV for the treatment of cancer, such as breast and prostate cancer.

Inventors:
YADAV VITTHAL (IN)
ATHAVALE MAITHILI (IN)
KHARKAR PRASHANT (IN)
SRIVASTAVA SANGEETA (IN)
SOMAIYA SAMIR (IN)
SATISH SMERA (IN)
GAVADE SANDIP (IN)
Application Number:
PCT/IN2018/050237
Publication Date:
January 03, 2019
Filing Date:
April 19, 2018
Export Citation:
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Assignee:
GODAVARI BIOREFINERIES LTD (IN)
International Classes:
A61K31/10; A61K31/357; A61K31/4025; A61K31/4709; A61K31/7048; A61P35/00; C07D401/14; C07H17/04
Domestic Patent References:
WO2012081038A22012-06-21
WO2015153653A12015-10-08
WO2010089778A22010-08-12
Foreign References:
EP2934549A22015-10-28
US20160068490A12016-03-10
US20130295207A12013-11-07
Other References:
SINGH RAJINDER ET AL: "Developing structure-activity relationships from an HTS hit for inhibition of the Cks1-Skp2 protein-protein interaction", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 25, no. 22, 30 September 2015 (2015-09-30), pages 5199 - 5202, XP029321424, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2015.09.067
YU ZHAO ET AL: "Synthesis and bioevaluation of novel arylnaphthalene lignans as anticancer agents", MEDICINAL CHEMISTRY RESEARCH, vol. 22, no. 5, 1 May 2013 (2013-05-01), pages 2505 - 2510, XP055154279, ISSN: 1054-2523, DOI: 10.1007/s00044-012-0245-1
YING WANG ET AL: "Synthesis and biological evaluation of novel lignan glycosides as anticancer agents", CHEMICAL BIOLOGY & DRUG DESIGN., vol. 88, no. 4, 1 October 2016 (2016-10-01), GB, pages 562 - 567, XP055486746, ISSN: 1747-0277, DOI: 10.1111/cbdd.12785
JIE HUI ET AL: "Synthesis and in vitro anticancer activities of novel aryl-naphthalene lignans", MEDICINAL CHEMISTRY RESEARCH, BIRKHĂ„USER-VERLAG, BOSTON, vol. 21, no. 12, 23 December 2011 (2011-12-23), pages 3994 - 4001, XP035126703, ISSN: 1554-8120, DOI: 10.1007/S00044-011-9937-1
JAKKA KAVITHA ET AL: "Juspurpurin, an unusual secolignan glycoside from Justicia purpurea", JOURNAL OF NATURAL PRODUCTS, 1 August 2003 (2003-08-01), United States, pages 1113 - 319, XP055515139, Retrieved from the Internet
ZHAO YU ET AL: "Synthesis of ether and arylacyl ester derivatives of diphyllin", CHINESE JOURNAL OF APPLIED CHEMISTRY - YINGYONG HUAXUE, KEXUE CHUBANSHE, CN, vol. 25, no. 11, 1 November 2008 (2008-11-01), pages 1315 - 1319, XP009508681, ISSN: 1000-0518
Attorney, Agent or Firm:
BASKARAN, Uma (IN)
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