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Patent Searching and Data


Title:
ANTISENSE NUCLEIC ACID TARGETING APOC3
Document Type and Number:
WIPO Patent Application WO/2021/193965
Kind Code:
A1
Abstract:
The present invention provides: an antisense oligomer having a base sequence represented by SEQ ID NO: 26, an antisense oligomer having a base sequence represented by SEQ ID NO: 26 with one to six bases substituted, deleted, inserted or added, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable hydrate thereof; an oligonucleotide conjugate resulting from the bonding of the foregoing and a molecule that can binds to asialoglycoprotein receptor; and a pharmaceutical composition that includes the foregoing.

Inventors:
SHIBA MARIKO (JP)
YAMAMOTO TSUYOSHI (JP)
WADA FUMITO (JP)
KOBAYASHI TADAYUKI (JP)
TACHIBANA KEISUKE (JP)
OBIKA SATOSHI (JP)
Application Number:
PCT/JP2021/013106
Publication Date:
September 30, 2021
Filing Date:
March 26, 2021
Export Citation:
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Assignee:
NAT CEREBRAL & CARDIOVASCULAR CT (JP)
UNIV OSAKA (JP)
International Classes:
C12N15/113; A61K31/712; A61K47/54; A61K48/00; A61P3/06; A61P43/00
Foreign References:
JP2016526874A2016-09-08
Attorney, Agent or Firm:
TAKASHIMA, Hajime (JP)
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