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Title:
ANTITHROMBOGENIC MATERIAL, PRODUCTION METHOD OF ANTITHROMBOGENIC MATERIAL, ARTIFICIAL ORGAN, AND ANTITHROMBOGENICITY IMPARTING AGENT
Document Type and Number:
WIPO Patent Application WO/2020/213529
Kind Code:
A1
Abstract:
The present disclosure provides an antithrombogenic material having a substrate and a surface modified layer provided on at least a portion of the substrate, wherein: the surface modified layer includes a block copolymer having a first structural unit having, in the side chain thereof, at least one selected from the group consisting of an alkylene chain and a halogenated alkylene chain, and a second structural unit represented by general formula (1); a unit including the first structural unit has a weight average molecular weight of 9,000-15,000; and a unit including the second structural unit has a weight average molecular weight of 10,000-40,000. In general formula (1), R1 represents a hydrogen atom or a methyl group, R2 represents a methyl group or an ethyl group, n represents an integer of 1-6, m represents an integer of 1-100, and x represents an integer of 1 or more.

Inventors:
TANAKA MASARU (JP)
YAO SHIGERU (JP)
HIRAI SHO (JP)
Application Number:
PCT/JP2020/016144
Publication Date:
October 22, 2020
Filing Date:
April 10, 2020
Export Citation:
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Assignee:
UNIV KYUSHU NAT UNIV CORP (JP)
UNIV FUKUOKA (JP)
International Classes:
C08F293/00; A61L27/34; A61L33/06
Domestic Patent References:
WO2016143787A12016-09-15
WO2017150000A12017-09-08
Foreign References:
US20100063570A12010-03-11
JP2015074633A2015-04-20
Other References:
YAO, SHIGERU: "Crystalline Supramolecular Interaction of Side Chain Crystalline Polymer and their Future", KOBUNSHI RONBUNSHU, vol. 73, no. 2, 2016, pages 139 - 146, XP055751073, ISSN: 0386-2186, DOI: 10.1295/koron.2015-0048
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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