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Patent Searching and Data


Title:
ANTITUMOR COMPOUND TARGETING IDH2 MUTATION AND METHOD OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/016523
Kind Code:
A1
Abstract:
The present application relates to compounds represented by general formula (I), general formula (II) or general formula (III), and pharmaceutically acceptable salts or hydrates thereof, preparation methods thereof, and pharmaceutical compositions thereof. The compounds represented by general formula (I), general formula (II) or general formula (III) have inhibitory activities against isocitrate dehydrogenase 2 (IDH2), thereby being capable of treating IDH2 mutation-induced cancers.

Inventors:
WANG SHULONG (CN)
ZHAO NA (CN)
LIU XIJIE (CN)
HU YUANDONG (CN)
ZHANG HUI (CN)
LUO HONG (CN)
PENG YONG (CN)
XIAO DENGMING (CN)
HAN YONGXIN (CN)
ZHANG XIQUAN (CN)
TIAN XIN (CN)
Application Number:
CN2016/092375
Publication Date:
February 02, 2017
Filing Date:
July 29, 2016
Export Citation:
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Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
LIANYUNGANG RUNZHONG PHARMACEUTICAL CO LTD (CN)
CENTAURUS BIOPHARMA CO LTD (CN)
International Classes:
C07D333/24; A61P35/00; A61P35/02; C07C275/42; C07D213/56; C07D231/12; C07D333/20; C07D409/10; C07D409/12
Domestic Patent References:
WO2014062511A12014-04-24
Foreign References:
Other References:
See also references of EP 3330263A4
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)
北京英赛嘉华知识产权代理有限责任公司 (CN)
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