Title:
APPARATUS AND METHOD FOR CRYSTALLIZING CULTURE SOLUTION USING PCA PROCESS
Document Type and Number:
WIPO Patent Application WO/2020/180101
Kind Code:
A3
Abstract:
Provided are an apparatus and method for crystallizing a culture solution using a PCA process. The method for crystallizing a culture solution using a PCA process comprises the steps of: supplying, to a container, a culture solution including a first solvent and a target material dissolved in the first solvent; supplying a third solvent to the container; and supplying a second solvent to the container. The first to third solvents form a multi-component mixture, and the target material precipitates. The apparatus for crystallizing a culture solution using a PCA process is an apparatus for acquiring a target material by drying a culture solution including a first solvent and the target material being dissolved in the first solvent, the apparatus comprising: a high-pressure container to which the culture solution is supplied; a first supply unit which is connected to the high-pressure container and supplies a second solvent to the high-pressure container; a second supply unit which is connected to the high-pressure container and supplies a third solvent; a pre-cooler which is provided adjacent to the first supply unit and pre-cools the second solvent discharged from the first supply unit; and a pre-heater which is provided adjacent to the high-pressure container and pre-heats the second solvent supplied to the high-pressure container.
Inventors:
LEE YOUNWOO (KR)
SON WONSU (KR)
PARK HEEJEONG (KR)
SONG SUNUK (KR)
KIM SINA (KR)
LEE CHANJU (KR)
SON WONSU (KR)
PARK HEEJEONG (KR)
SONG SUNUK (KR)
KIM SINA (KR)
LEE CHANJU (KR)
Application Number:
PCT/KR2020/003048
Publication Date:
May 14, 2021
Filing Date:
March 04, 2020
Export Citation:
Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
International Classes:
A01N1/02; C12N5/00
Foreign References:
| US9259396B2 | 2016-02-16 | |||
| US6838089B1 | 2005-01-04 | |||
| US9138705B2 | 2015-09-22 | |||
| KR101107328B1 | 2012-01-20 | |||
| KR100600691B1 | 2006-07-19 |
Other References:
FUSARO, F. ET AL.: "Compressed CO2 antisolvent precipitation of lysozyme", THE JOURNAL OF SUPERCRITICAL FLUIDS, vol. 49, 2009, pages 79 - 92, XP026048780, DOI: 10.1016/j.supflu.2008.12.005
Attorney, Agent or Firm:
KANG, Moonho (KR)
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