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Title:
APPARATUS AND METHOD FOR SPECIFIC RELEASE OF CAPTURED EXTENSION PRODUCTS
Document Type and Number:
WIPO Patent Application WO2002010373
Kind Code:
A3
Abstract:
Apparatus and methods for separating different polynucleotide populations in a mixture are provided, wherein different polynucleotides or polynucleotide populations are captured on different solid support. After hybridization, polynucleotides are selectively released from a selected support by altering a physical property of that support. The released polynucleotides can be eluted from a common flow path and isolated.

Inventors:
SHIGEURA JOHN
CHEN JER-KANG
Application Number:
PCT/US2001/022789
Publication Date:
February 06, 2003
Filing Date:
July 17, 2001
Export Citation:
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Assignee:
PE CORP NY (US)
International Classes:
C12N15/10; C12Q1/68; C12Q1/6834; G01N30/46; G01N30/60; C07B61/00; G01N1/34; G01N30/02; G01N30/30; G01N30/50; G01N30/52; G01N30/56; (IPC1-7): C12N15/10; C12Q1/68; C07H1/08; B01D15/08; B01L3/00
Domestic Patent References:
WO1998014610A21998-04-09
WO2000031304A12000-06-02
WO1996002836A11996-02-01
Foreign References:
US5527670A1996-06-18
US5846719A1998-12-08
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