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Title:
APPLICATION OF 2,4-DIHYDROXYBENZOIC ACID OR ISOMER THEREOF IN RELATED DISEASES OR CONDITIONS CAUSED BY IRON OVERLOAD
Document Type and Number:
WIPO Patent Application WO/2021/057680
Kind Code:
A1
Abstract:
Disclosed is an application of 2,4-dihydroxybenzoic acid or an isomer thereof in foods, health products or medicines for treating or preventing related diseases or conditions caused by iron overload. The isomer of the 2,4-dihydroxybenzoic acid is selected from 2,3-dihydroxybenzoic acid, 2,5-dihydroxybenzoic acid, 3,4-dihydroxybenzoic acid and 3,5-dihydroxybenzoic acid. The design is reasonable, and direct administration of the 2,4-dihydroxybenzoic acid and isomer thereof is employed to achieve the aim of directly reducing the "iron ions" in the non-protein complexed iron in cells, so as to quickly remove excess iron from the body to achieve the purpose of treating various related diseases (especially diabetes) caused by iron overload.

Inventors:
ZHANG JIANGUO (CN)
REN WUXIAN (CN)
HAN YINGBING (CN)
YA BANGQIN (CN)
Application Number:
PCT/CN2020/116613
Publication Date:
April 01, 2021
Filing Date:
September 21, 2020
Export Citation:
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Assignee:
ZHANG JIANGUO (CN)
REN WUXIAN (CN)
HAN YINGBING (CN)
YA BANGQIN (CN)
YABAO PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
A23L33/10; A61K31/192; A61P1/16; A61P3/06; A61P3/10; A61P7/00; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P19/02; A61P19/06; A61P25/24; A61P25/28; A61P29/00; A61P31/20; A61P35/00
Domestic Patent References:
WO2007026028A22007-03-08
Foreign References:
CN1401318A2003-03-12
CN1649577A2005-08-03
CN103340880A2013-10-09
CN101990399A2011-03-23
Other References:
IVANA BRZONOVA ET AL.: "Enzymatic synthesis of catechol and hydroxyl-carboxic acid functionalized chitosan microspheres for iron overload therapy.", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS., no. 79, 7 May 2011 (2011-05-07), XP028391546
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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