Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
APPLICATION OF COMPOUND OR TRADITIONAL CHINESE MEDICINE EXTRACT IN PREPARATION OF NUCLEIC ACID DELIVERY AGENT AND RELATED PRODUCTS THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/177383
Kind Code:
A1
Abstract:
The present application relates to extracting, from a traditional Chinese medicine, a plurality of compounds capable of prompting nucleic acid delivery or synthetic compounds, and promoting nucleic acid such as sRNA to absorb and enter a target cell using the extracted compounds or a plurality of combinations and promoting the nucleic acid to enter required target sites in vivo of an object.

Inventors:
JIANG CHENGYU (CN)
DU JIANCHAO (CN)
LIANG ZHU (CN)
LI XIAOYUN (CN)
Application Number:
PCT/CN2018/081155
Publication Date:
October 04, 2018
Filing Date:
March 29, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
INST BASIC MEDICAL SCIENCES CAMS (CN)
International Classes:
A61K48/00; C07C219/00; C07C229/00; C07C233/00; C07F9/09
Domestic Patent References:
WO2008103276A22008-08-28
WO2009129387A22009-10-22
WO2009129385A12009-10-22
WO2009129395A12009-10-22
Foreign References:
JP2013245190A2013-12-09
Other References:
CHILLEMI, ROSA.: "Oligonucleotides Conjugated to Natural Lipids:Synthesis of Phosphatidyl-Anchored Antisense Oligonucleotides", BIOCONJUGATE CHEMISTRY, vol. 24, no. 4, 201300315, pages 648 - 657, XP055132684, DOI: 10.1021/bc300602g
See also references of EP 3604269A4
Attorney, Agent or Firm:
LIU, SHEN & ASSOCIATES (CN)
Download PDF: